نتایج جستجو برای: mrna levels

تعداد نتایج: 1014867  

1994
J F Alderete ALI KHOSHNAN

A Khoshnan and J F Alderete phenotypically variable immunogen mRNA. RNA virus has upregulated levels of Trichomonas vaginalis with a double-stranded

Journal: :American journal of physiology. Endocrinology and metabolism 2003
Bin Bao Ananda S Prasad Frances W J Beck Michele Godmere

Zinc plays an important role in cell-mediated immune function. Altered cellular immune response resulting from zinc deficiency leads to frequent microbial infections, thymic atrophy, decreased natural killer activity, decreased thymic hormone activity, and altered cytokine production. In this study, we examined the effect of zinc deficiency on IL-2 and IFN-gamma in HUT-78 (Th0) and D1.1 (Th1) c...

2003
Daniel Goldman Hans R. Brenner Stephen Heinemann

Denervation of adult skeletal muscle results in increased sensitivity to acetylcholine in extrajunctional regions of the muscle fiber. This increase in acetylcholine sensitivity is accompanied by a large increase in the level of mRNAs coding for the a-, f3-, Y-, and S-subunits of the acetylcholine receptor. To determine whether muscle activity is sufficient to regulate expression of extrajuncti...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه گیلان - دانشکده زیست شناسی 1393

nef یکی از پروتئین های همراه در hiv است که برای همانند سازی ویروس در سلول های میزبان در طول عفونت ویروسی ضروری است. با توجه به جای گیری nef در غشای اندوزمی و پلاسمایی و اثر تحریک کننده ی آن بر خروج خود از طریق آزادسازی اگزوزم ها، و نیز اثر کاهنده ی آن بر سلول های cd4+، هدف از این مطالعه کلونینگ و بیان ژن nef ویروس hiv به منظور تهیه ی پروتئین nef نوترکیب بود. به این منظور سلول های بیان کننده ی پ...

Background: The Endothelial PAS domain-containing protein 1 (EPSA1) is the key transcriptional regulator of hypoxic response and Vascular Permeability Factor (VPF) is an important growth factor for vascular development and angiogenesis. OBJECTIVES: In the present study, the levels of the EPSA1 coding gene and VPF transcripts were evaluated during Larval development of Beluga, Huso huso. METHODS...

Gholamhossein Hassanshahi, Mohammad Kazemi Arababadi, Mohammad Momeni Mohammad Reza Mirzaei Nahid Zainodini

Background: Absent in Melanoma 2 (AIM2) is an intracellular microbial dsDNA sensor which plays an important role in production of proinflammatory cytokines through Apoptosis associated Speck-like protein containing a Caspase activation and recruitment domain (ASC) and Caspase-1. Micro-RNAs (miRNAs) play important roles in regulation of immune related genes. However, there is little information ...

Journal: :progress in biological sciences 2011
mehrzad roghani fereidoun mahboudi mohammad ali sahraian masoud etemadifar elahe elahi

il-32 and tnf? are important cytokines in autoimmune and inflammatory diseases. il-32 has not been previously studied with respect to ms. here, we report il-32 and tnf? transcript levels in peripheral blood mononuclear cells of ms patients and control individuals by real time pcr. a significant difference in il-32 and tnf? mrna levels of patients as compared to controls was not observed. howeve...

Journal: :acta medica iranica 0
mozhgan moogooei department of immunology, rafsanjan university of medical sciences, rafsanjan, iran. masoud shamaei pediatric respiratory diseases research center, national research institute of tuberculosis and lung diseases (nritld), shahid beheshti university of medical sciences, tehran, iran. hossein khorramdelazad molecular medicine research center, rafsanjan university of medical sciences, rafsanjan, iran. shirin fattahpour department of biochemistry, rafsanjan university of medical sciences, rafsanjan, iran. seyed mohammad seyedmehdi pediatric respiratory diseases research center, national research institute of tuberculosis and lung diseases (nritld), shahid beheshti university of medical sciences, tehran, iran. maryam moogooei department of immunology, shahid sadoughi university of medical sciences and health services, yazd, iran

chemokines are biologically active peptides involved in the pathogenesis of various pathologies including brain malignancies. they are amongst primitive regulators of the development of immune responses against malignant glial tumors. the present study aimed to examine the expression of cc chemokines in anaplastic astrocytoma and glioblastoma multiform patients at both mrna and protein levels. ...

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