UNLABELLED Neuroglial heterotopia is a rare congenital anomaly that mostly involves the head and neck region. We report a female fetus with multicentric paraspinal neuroglial heterotopia in the retropharyngeal and retroperitoneal spaces, right renal agenesis, left renal hypoplasia, and Müllerian agenesis. Additional findings included bilateral preaxial polydactyly of the hands, megacystis, rect...

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital disorder marked by aplasia or hypoplasia of the uterus and vagina as result arrest in development müllerian ducts. Prevalence being 1 4000–5000 live births females. Leiomyoma most common uterine tumor, their occurrence from rudimentary females with MRKH very rare only few cases have been documented literature. Here we report 38-year...

Vaginal dilation is proposed as the first choice treatment for patients with vaginal aplasia, but many patients with MRKH or Rokitansky syndrome (and cases with CAIS) may require a vaginoplasty. It is also necessary to make vaginoplasty in patients with vaginal or cervicovaginal atresia with a functional uterus before performing an utero-neovaginal anastomosis, also in trans-sexual men.

BACKGROUND: Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a rare disorder described as aplasia or hypoplasia of uterus and vagina due to an early arrest in the development Mullerian ducts. The etiology MRKH remains uncertain: Although at beginning, it was mentioned that this result sporadic abnormalities. It has recently been assumed genetic background cause increasing number familial cases...

BACKGROUND Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is characterized by congenital aplasia of the uterus and the upper part of the vagina in women showing normal development of secondary sexual characteristics and a normal 46, XX karyotype. The uterovaginal aplasia is either isolated (type I) or more frequently associated with other malformations (type II or Müllerian Renal Cervico-thorac...

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a pathological condition characterized by primary amenorrhea and infertility and by congenital aplasia of the uterus and of the upper vagina. The development of secondary sexual characters is normal as well as that the karyotype (46,XX). Etiologically, this syndrome may be caused by the lack of development of the Müllerian ducts between the fift...

The Gram-negative bacterial pathogen Klebsiella pneumoniae forms biofilms to facilitate colonization of biotic and abiotic surfaces. The formation of biofilms by K. pneumoniae requires the expression of type 3 fimbriae: elongate proteinaceous filaments extruded by a chaperone-usher system in the bacterial outer membrane. The expression of the mrkABCDF cluster that encodes this fimbrial system i...

Various congenital anomalies of the mullerian system have so far, been described. Our case with MRKH syndrome had two rudimentary horns, and had also a leiomyoma arising from the left rudimentary horn. The patient was presented to our department because of primary amenorrhoea and infertility. Clinical examination revealed a blind vaginal pouch of 3 cm in size and mass was palpated in the left a...