نتایج جستجو برای: moxonidine

تعداد نتایج: 185  

Journal: :Revista ciencia médica 2022

Introduction: The aim of this study was to analyze the medication used by patients with hypertensive crisis (blood pressure above 180/120mmHg) and its impact on main risk factors for emergency development. Methods: A total 233 (108 male, 125 female), 184 had urgency/ 53 (54.44% /50.95% in women) at Emergency department during 11 months. Patients were divided five age groups as decades starting ...

2003
WALTER RAASCH BRITTA JUNGBLUTH ULRICH SCHÄFER WALTER HÄUSER PETER DOMINIAK

It is known that moxonidine acts as an agonist at presynaptic 2-adrenoceptors of the postganglionic sympathetic nerve terminals and leads to a reduction in noradrenaline release. In addition, it is conceivable that I1-binding sites located in other regions of the preand postganglionic sympathetic neurons are involved in this effect. Our aim was to investigate whether and to what extent activati...

Journal: :Brain Research 2015
Gláucia M.F. Andrade-Franzé Carina A.F. Andrade Silvia Gasparini Laurival A. De Luca Patrícia M. De Paula Débora S.A. Colombari Eduardo Colombari José V. Menani

The lateral parabrachial nucleus (LPBN) and the central nucleus of the amygdala (CeA) are important central areas for the control of sodium appetite. In the present study, we investigated the importance of the facilitatory mechanisms of the CeA on NaCl and water intake produced by the deactivation of LPBN inhibitory mechanisms. Male Holtzman rats (n=7-14) with stainless steel cannulas implanted...

Journal: :Current Controlled Trials in Cardiovascular Medicine 2004
Cornel Pater Deepak Bhatnagar Jean-Pascal Berrou Joachim Luszick Katrin Beckmann

Hypertension and diabetes mellitus are closely interrelated and coexist in as many as two-thirds of patients with type 2 diabetes. The consequent risk of such an association is an accelerated development of atherosclerotic cardiovascular disease and nephropathy complications.In choosing an antihypertensive agent, effectiveness needs to be accompanied by favourable metabolic, cardioprotective, a...

Journal: :British Journal of Clinical Pharmacology 2002

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