We have separated for enzyme analysis the following layers that surround the conceptus at midgestation: decidua, trophoblast, parietal endoderm (including Reichert's membrane), visceral endoderm, yolk-sac mesoderm and amnion. Measurement of several catabolic enzyme activities (N-acetyl-beta, D-hexosaminidase, beta-glucuronidase, alkaline and acid phosphatases and non-specific esterases) in thes...

The observation that adenomas develop very rapidly in the pulmonary tissue of mouse embryos implanted together with methylcholanthrene, in adult animals, has led to tests of the neoplastic potentialities of this tissue in utero. C strain females in the latter half of pregnancy were injected with urethane and the lungs of their young were searched for adenomas. None could be perceived with certa...

This paper develops some existing ideas in FCA to provide an analysis of a large data set of mouse embryo gene expressions. It develops new techniques for managing complexity and visualisation in FCA to identify and approximate large groups of co-expressed genes. This work has been carried out as part the European CUBIST Project: http://www.cubist-project.eu/

Abstract Spexin (SPX) is a pleiotropic peptide with highly conserved protein sequence from fish to mammals and its biological actions are mediated by GalR2/GalR3 receptors expressed in target tissues. Recently, SPX was found be novel satiety factor models but whether the has similar function still unknown. Using mouse as model for mammalian species, functional role of feeding control mechanisms...

Telomere shortening and telomerase activation in human somatic cells have been implicated in cell immortalization and cellular senescence. To further study the role of telomerase in immortalization, we assayed telomere length and telomerase activity in primary mouse fibroblasts, in spontaneously immortalized cell clones, and in mouse tissues. In the primary cell cultures, telomere length decrea...

objective(s) galectin-3 (gal-3) is a member of the b-galactoside-binding lectins which is expressed in a variety of tissues and plays a role in diverse biological events, such as embryogenesis, adhesion, cellular proliferation, and apoptosis. in this study, the presence and distribution of galectin-3 (gal-3) in the mouse testicular tissue was investigated. materials and methods eight adult nmri...