To evaluate the expression of miR-155 and autophagy in COPD related mechanism. Alveolar macrophages were extracted from patients. dynamic mouse model was established. Mouse alveolar also isolated cultured. Rat macrophage cell line NR8383 introduced. The TLR4 NF-κB cells with CSE treatment evaluated. upregulated bronchoalveolar lavage fluid patients, treated (p < 0.05). Overexpression miR‐155 le...

Background: Lead is a heavy metal that has been known for its adverse effects on many body organs and systems and. In the present study, the protective effect of green tea (GTE) on the male reproductive system following the administration of lead (pb) was investigated. Materials and Methods: Forty male NMRI mice were divided into four groups of 10 animals each. Controls, GTE treated, pb treated...

Background: The purpose of this study was to evaluate the effect of Ruta graveolens (RG) Aqueous Extract on in vitro fertilization (IVF) rate and embryo development. RG, commonly called sudab or rue, has been known as a medical plant since ancient times. Recently some medicinal properties were reported for RG such as: antioxidant, anti-inflammatory, anti-tumor, anti-androgenic, anti- conceptive...

Background: Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis. New procedure such as sound wave especially low intensity ultrasound (LIUS) can be effective on increasing the number of cells. In this study we investigated the effect of LIUS stimulation on mouse SSCs. Materials and Methods: Isolated SSCs from neonate mice cultured in DMEM culture medium with 10% fetal bovine ...

Effective protocols are introduced for parthenogenesis activation in oocytes. Hydrostatic pressure can act as a mechanical stimulator that rearranges egg contents, leading to new structural or molecular combination. Alternatively, mechanical stimulation could stimulate a mechanically-gated process, such as opening or closing of stretch activated ion channels. This study, investigated the use of...