background: considerable attention is focused on effects of electromagnetic field (emf) and its increasing use in everyday life. appliances and various equipments are sources of electromagnetic fields with a wide-range of technical characteristics. objective: in this study we investigated the effect of emf (50 hz, 0.5 mt) on epididymis and deferens duct in mice. materials and methods: 30 balb/c...

background: a new biological dosimeter based on methemoglobin level was developed in this study. materials and methods: methemoglobin level in erythrocytes from mice subjected to γ rays from a 60co source was detected using the methemoglobin kit. the dose range was from 0.5 to 8 gy and the dose rate was 0.5 gy/min. results: the results demonstrate that methemoglobin level increases with increas...

background: giardia has the ability to infect many mammals including dogs, cats, deer, mice, ground squirrels, chinchillas, swine, rabbits, pocket mice, oxen, guinea pigs, and humans. giardia lamblia (also giardia duodenalis, g.intestinalis) isolates have been variably divided into two or three genotypes by different investigators, and each group can be divided into subgroups. objectives: we ha...

abstractalthough the biokinetics, metabolism, and chemical toxicity of uranium are well known, until recently little attention was paid to the potential toxic effects of uranium on reproduction and development in mammals. in recent years, it has been shown that uranium is a developmental toxicant when given orally or subcutaneously (sc) to mice. decreased fertility, embryo/fetal toxicity includ...

litis study is based on embryotoxic effects of ethanol on embryos and discussing the morphologic and hhtahtgic changes and defects an mouse. tlie female animals were divided in three groups. hie first group untreated as a control group but the second and third group received 10% and 20% solutions of ethanol respectively. animals get use to certain level of ethanol solution and in the 10th day, ...

temporary paralysis is a rare manifestation of envenoming following the yellow iranian scorpion, odontobuthus doriae (o. doriae). thus, to elucidate the underlying mechanism, we investigated the neurotoxic effect of venom in the sciatic nerve, the possible mechanism in a mice model. the neurotoxicity and temperature effects in the venom-induced neurotoxicity were examined using the mouse sciati...

background: leukemia inhibitory factor (lif) is a pleiotropic cytokine of interleukin-6 family with a remarkable range of biological actions such as proliferative effects on the granulosa and theca cells. the aim of this study was to evaluate the effects of lif on the growth and maturation of mouse fresh and vitrified preantral follicles, an in vitro model was developed. methods: the ovaries of...

background: in vitro maturation (ivm) of oocytes is a promising technique to reduce the costs and avert the side-effects of gonadotropin stimulation for in vitro fertilization (ivf). the pregnancy rates from oocytes matured in vitro are much lower than those of in vivo stimulation cycles, indicating that optimization of ivm remains a challenge. objective: in this study, we investigated the effe...

background: since embryonic stem (es) cells have the dual ability to proliferate indefinitely and differentiate into multiple tissue types, es cells could potentially provide an unlimited cell supply for human transplantation. objective: in order to study the differentiation of mouse embryonic stem (mes) cells, they were cultured in suspension by using es media without leukemia inhibitory facto...

Despite a lot of research, the etiology and progression of breast cancer remain incompletely understood. Recently, human cytomegalovirus (HCMV) was reported as a risk factor for breast cancer. The aim of this study was to know whether breast cancer could be caused by cytomegalovirus or not? In this experiment seventeen samples of RAZI/A mice with spontaneous breast cancer were being gathered fr...