Industry trends aimed at integrating higher levels of circuit functionality have triggered a proliferation of mixed analog-digital systems. Magnified noise coupling through the common chip substrate has made the design and verification of such systems an increasingly difficult task. In this paper we present a new method based on a precorrected-DCT algorithm that extends an eigendecomposition-ba...

1. Abstract This paper presents a modeling technique to be used in substrate coupling computation of mixed-signal circuits. Substrate crosstalk can negatively impact the performance of analog circuit elements such as mixers or amplifiers and can lead to a total breakdown of circuit parts. In order to forecast substrate-related problems and to analyze its influence EDA-tools are needed that can ...

Microelectronics is heading towards larger and larger systems implementedon a single chip. In wireless communication equipment, e.g., cellular phones,handheld computers etc., both analog and digital circuits are required. Ifseveral integrated circuits (ICs) are used in a system, a large amount of thepower is consumed by the communication between the ICs. Furthermore, thecomm...

In modern monolithic integrated circuits, substrate coupling is a major concern in mixed-mode systems design. Noise injected into the common substrate by fast switching digital blocks may affect the correct functioning or performance of the overall system. Verification of such systems implies the availability of accurate and simulation-efficient substrate coupling models. For frequencies up to ...

Mixed-substrate microbial growth is among the most intensely studied systems in molecular microbiology. Several mathematical models have been developed to account for the genetic regulation of such systems, especially those resulting in diauxic growth. In this work, we compare the dynamics of three such models (Narang, Biotech. Bioeng., 59, 116, 1998; Thattai&Shraiman, Biophys. J, 85, 744, 2003...

The lignocellulosic biomass (especially agricultural wastes) is known to be an excellent carbon source for microbial enzyme production. In this paper, the cellulase production from lignocellulosic materials under solid state fermentation (SSF) was investigated. The effects of fermentation conditions, such as moisture content, initial pH, temperature, and composition of mixed substrate (wheat st...

Substrate noise generated by digital circuits on mixed-signal ICs can disturb the sensitive analog/RF circuits, such as Low Noise Amplifier (LNA), sharing the same substrate. This paper investigates the adverse impact of the substrate noise on a high frequency cascode LNA laid out on a lightly doped substrate. By studying the major noise coupling mechanisms, a new and efficient modeling method ...

An innovative theoretical approach that enables the complete characterisation of enzyme– substrate and enzyme–substrate–competitor reactions is generalised to systems with multiple alternative substrates. Based on the quasi-steady-state assumption, time-dependent closed form solutions are presented for cases with even, weak and mixed substrate competition. The analytic framework should facilita...

Enzymic catalysts of thiol:disulfide oxidoreduction contain two cysteine residues in their active sites. Another common residue is an aspartate (or glutamate), the role of which has been unclear. Escherichia coli thioredoxin (Trx) is the best characterized thiol:disulfide oxidoreductase, and in Trx these three active-site residues are Cys32, Cys35, and Asp26. Structural analyses had indicated t...

An integral equation approach with a new solution procedure using moment method (MoM) is applied for the computation of coupled currents on the surface of a printed dipole antenna and inside its high-permittivity three-dimensional dielectric substrate. The main purpose of this study is to validate the accuracy and reliability of the previously proposed MoM procedure by authors for the solution ...