This account focuses on the application of ω-transaminases, lyases, and oxidases for the preparation of amines considering mainly work from our own lab. Examples are given to access α-chiral primary amines from the corresponding ketones as well as terminal amines from primary alcohols via a two-step biocascade. 2,6-Disubstituted piperidines, as examples for secondary amines, are prepared by bio...

Highly fluorescent and photoconductive nanoribbons assembled from an asymmetric perylene diimide (PDI) were used as a dual-mode sensor for sensitive and selective discrimination of two classes of organic amines in the vapor phase, i.e., alkyl amines and aromatic amines.

Biological amines are nitrogenous compounds that occur naturally in wide variety of food. Histamine, putrescine, cadavarine, tyramine, spermine, spermidine, tryptamine and β-phenylethylamine are the biogenic amines that are normally present in foods. Although the biogenic amines play some important physiological functions but high level of amines can cause toxicological effects. High amount of ...

The synthesis of a series of benzimidazole-N-benzylpropan-1-amines and adenine-N-benzylpropan-1-amines is described. Subsequent evaluation against two strains of the anaerobic bacterium Clostridium difficile was performed with three amine derivatives displaying MIC values of 16 μg/mL. Molecular docking studies of the described amines determined that the amines interact within two active site po...

Azo dyes in textiles may release aromatic amines after enzymatic cleavage by skin bacteria or after dermal absorption and metabolism in the human body. From the 896 azo dyes with known chemical structure in the available textile dyes database, 426 azo dyes (48%) can generate one or more of the 22 regulated aromatic amines in the European Union in Annex XVII of REACH. Another 470 azo dyes (52%) ...

A homologue series of aliphatic streptomycylamines (SM-amines) have been prepared and tested in vitro (binding to 70S ribosomes) and in vivo (MIC). The short-chain SM-amines act as streptomycin (SM) but are less active than SM. They are inactive towards a SM-resistant Escherichia coli, our strain 042. The long-chain SM-amines are active both towards our sensitive and resistant E. coli, our s...

The sorption affinity of eighty-six charged amine structures to phospholipid monolayers (log KIAM) was determined using immobilized artificial membrane high-performance liquid chromatography (IAM-HPLC). The amine compounds covered the most prevalent types of polar groups, widely ranged in structural complexity, and included forty-seven pharmaceuticals, as well as several narcotics and pesticide...

Soil-induced oxidation and subsequent polymerization of aromatic amines is an important pathway for reducing the mobility of amines in soils and their hazard potential in the environment. This study assesses the hypothesis that manganese(III/IV) oxides/hydroxides play a significant role in the oxidation of aromatic amines in whole soils. Aromatic amines including alpha-naphthylamine, p-methoxya...

Aliphatic primary amines are industrial chemicals with a wide variety of applications. For the determination of these substances, HPLC has recently been used; it has several advantages over other analytical methods, including high selectivity and sensitivity. On the other hand, an electrochemiluminescence (ECL) method has been developed as a highly sensitive method for HPLC detection.)-3 Howeve...

The phenolic amines include substances such as epinephrine, norepinephrine, and serotonin, whose physiological importance has been known for many years, and some other amines of recent interest whose biological significance is less clear; these include dopamine (1) and octopamine (2). It is probable that still others exist and have a physiological function in some tissues of the body. The conce...