Mullerian Inhibiting Substance (MIS) functions to promote regression of the Mullerian duct during male development. Maintaining the sexually dimorphic pattern of MIS expression is essential for proper mammalian reproductive tract development. Here, we show that the intricate spatial and temporal pattern of MIS expression is directed by a remarkably small proximal promoter of only 180 base pairs...

BACKGROUND Kinematic design is a predominant phase in the design of robotic manipulators for minimally invasive surgery (MIS). However, an extensive overview of the kinematic design issues for MIS robots is not yet available to both mechanisms and robotics communities. METHODS Hundreds of archival reports and articles on robotic systems for MIS are reviewed and studied. In particular, the kin...

The rapid advancements in information technology and the global economic crisis have affected the MIS job market. Recruiters are no longer looking for Grade Point Average as a hiring criterion. New skill sets has been adapted by human resource departments with respect to hiring new MIS graduates. Keeping up to date with these new changing and rapidly growing skills is a continuous and challengi...

The MIS data is critical to an organization and should be protected from misuse by wrong persons. Although The MIS data is typically meant for the senior managers each MIS report may not be required by every manager. The access to MIS data is determined by the role of an individual in the organization and controlled by the MIS administrator accordingly. The access is generally determined by the...

The MIS (Management Information Systems) Project, is a national initiative installing a common Library and Academic Management system in fifteen Institutes of Technology in Ireland.1 Its role is to manage the selection, implementation, and development of software installations in key business areas. These areas include student registration, personnel, financial administration and library manage...

The stratification among journals constituting the formal communication system for MIS research is described and analyzed on the basis of MIS experts' opinions, published MIS articles, and citation frequency. Implications of the research results are discussed for authors seeking suitable publication outlets, for academic administrators making promotion decisions, for editors wishing to establis...

Müllerian Inhibiting Substance (MIS) expression is inversely proportional to the serum concentration of testosterone in males after birth and in vitro studies have shown that MIS can lower testosterone production by Leydig cells. Also, mice overexpressing MIS exhibited Leydig cell hypoplasia and lower levels of serum testosterone, but it is not clear whether this is a result of MIS affecting th...

BACKGROUND Pre-antral and early antral follicles secrete Müllerian inhibiting substance (MIS), suggesting that MIS may directly reflect ovarian reserve. Since little is known about how ovarian reserve affects oocyte quality, we attempt here to assess the predictive value of MIS on embryo morphology and IVF outcome. To do so, we measured MIS at the time of HCG administration 36 h prior to oocyte...

BACKGROUND The objective of this study was to investigate the effects of Rosiglitazone (RSG) infusion therapy following minimally invasive surgery (MIS) for intracerebral hemorrhage(ICH) evacuation on perihematomal secondary brain damage as assessed by MMP-9 levels, blood-brain barrier (BBB) permeability and neurological function. METHODS A total of 40 male rabbits (2.8-3.4 kg) was randomly a...

BACKGROUND Minor ischemic stroke (MIS) represents a major global public health problem worldwide due to high incidence. The aim of this study was to investigate whether metabolic syndrome (MetS) is a strong risk for MIS and subsequent vascular events (SVE). METHODS A retrospective cohort study was performed examining symptomatic MIS in a Chinese neurologic outpatient population aged over 25 y...