Migraine without aura is frequently reported in female patients with irritable bowel syndrome (IBS), but knowledge about the relationship between these two conditions is still lacking. This study was aimed to explore the particularities of migraine without aura in young female patients with IBS in order to establish a possible link between them. From a cohort of young female patients hospitaliz...

Almost all Unani physicians have advocated Nutool therapy in the management of migraine (Shaqiqa), particularly with or without medicated oil liquid, but unfortunately these not evaluated on scientific parameters. Despite fact that, this is practice physician and a large number patients been treated successfully; regimen still requires validation to generalize their popularity acceptability. Pr...

BACKGROUND Migraine is a prevalent and debilitating disease that may, in part, arise because of disruption in neurovascular endothelia caused by elevated homocysteine. This study examined the homocysteine-lowering effects of vitamin supplementation on migraine disability, frequency and severity and whether MTHFRC677T genotype influenced treatment response. METHODS This was a randomized, doubl...

OBJECTIVE To investigate the cost-effectiveness and cost-benefit of initiating sumatriptan therapy in patients with acute migraine who were previously taking nontriptan drugs. PATIENTS AND METHODS This is an economic analysis of a prospective, pretest-posttest, observational 6-month outcomes study of 178 patients with a physician diagnosis of migraine who received their first prescription for...

The goals of acute treatment of migraine are cost-effective rapid relief, consistent reduction of disability, and reduced use of rescue medications. Key to acute treatment is matching medication to disability as a surrogate marker for disease severity with a stratified care approach. In the absence of vascular contraindications, triptans are first-line acute treatments for disabling migraine. A...

OBJECTIVE The purpose of this study was to assess psychometric properties of the six-item Headache Impact Text (HIT-6™) across episodic and chronic migraine. METHODS Using a migraine screener and number of headache days per month (HDPM), participants from the National Survey of Headache Impact (NSHI) study and the HIT-6 validation study (HIT6-V) were selected for this study. Eligible particip...

Introduction: Wet-Cupping Therapy (WCT) is an ancient method used in several indications, particularly for incurable disorders such as migraine. The aim of this study was to investigate the impact of WCT on migraine. Materials and methods: The study included 78 patients diagnosed with migraine headache, and evaluations were made before and after WCT. Each patient underwent WCT three times at ap...

abstract background some researches have shown the association between iron deficiency and migraine headache in adults. the aim of present study was to evaluate efficacy of ferrous sulfate treatment on migraine headaches of 5-15 years old migraineur children with iron deficiency. materials and methods in a quasi- experimental study, monthly frequency, severity, duration and disability of headac...