Evidence-based medicine is the backbone of modern medicine. Any newly proposed therapy needs to be tested in high-quality randomised controlled trials (RCTs) before being considered for approval. Nepal a low-income country south Asia. Researchers have been contributing global health by doing RCTs high-altitude and infectious diseases like typhoid. Infectious such as tuberculosis, typhus, leptos...

Background A significant number of cardiovascular disease (CVD)-related deaths occur in developing countries. An increasing prevalence of CVD is associated with a change in the macro-economy of these countries. In this post hoc analysis, CVD risk factor (CVDRF) prevalence is evaluated across countries based on national income in the Africa and Middle East Region (AfME). Methods Data from the ...

OBJECTIVE To compare availability, urban price, and affordability of child/family safety devices between 18 economically diverse countries. DESIGN Descriptive: urban price surveys by local safety organisations or shoppers. SETTING Retail stores and internet vendors. MAIN OUTCOME MEASURES Prices expressed in US dollars, and affordability measured by hours of factory work needed to buy a ch...

There is a significant emerging burden of chronic and end-stage kidney disease in low- and middle-income countries, driven by population ageing and the global epidemic of type 2 diabetes. Sufferers of end-stage kidney disease require ongoing dialysis or kidney transplantation to survive; however, in many low- and middle-income countries, treatment options are strictly limited or unaffordable. L...

OBJECTIVE Middle-income countries are often referred to as developing or emerging economies and face multiple challenges of severe financial stresses in their health care sectors, and high disease burden. The objective of this study is to provide an overview of how health technology assessment (HTA) is used and organized in selected middle-income countries and its role in the process of pharmac...