1. An extracellular, proteolytic enzyme has been observed in more than 30 strains of beta type, aerobic and facultative hemolytic streptococci. 2. The enzyme is readily demonstrable in sterile filtrates of cooked meat cultures. 3. No gas or foul odor is produced. 4. It is partially inactivated by exposure to about 60 degrees C. for 45 minutes or longer. 5. The enzyme manifests itself in cooked ...

The isopycnic equilibrium of [131J]albumin digesting particles from mouse liver homogenates occurs, in a sucrose gradient, at a density 1.25, and it does not change with time after albumin injection (5 to 300 minutes).

This study investigated the possibilities of improving methane yield production from, the anaerobic co-digestion of wheat straw (WS) and primary sludge (PS). The batch experiment was conducted under mesophilic conditions. Different mixtures of WS and PS depending on its C/N ratio were carried out to investigate the optimum C/N ratio for effective methane production. The cumulative methane yield...

Studies in this and other laboratories have disclosed a variety of starch-digesting rumen organisms, including Streptococcu bouis (Hungate et al., 1952), several cellulolytic strains (Hungate, 1950), and various non-cellulolytic bacteria (Gall et al., 1947; Gall and Huhtanen, 1951; Huhtanen and Gall, 1953a, b; Bryant and Burkey, 1953a,b; Jayko, 1953; McPherson, 1953; van der Wath, 1948) as well...

Candida albicans is the most common fungal pathogen of humans and has developed an extensive repertoire of putative virulence mechanisms that allows successful colonization and infection of the host under suitable predisposing conditions. Extracellular proteolytic activity plays a central role in Candida pathogenicity and is produced by a family of 10 secreted aspartyl proteinases (Sap proteins...

Mutational experiments were carried out to decrease the protease productivity of Aspergillus ficum IFO 4320 by using N-methyl-N'-nitro-N-nitrosoguanidine. A protease-negative mutant, M-33, exhibited higher alpha-amylaseactivity than the parent strain under submerged culture at 30 degrees C for 24 h. About 70% of the total alpha-amylase activity in the M-33 culture filtrate was adsorbed onto sta...

New work in Caenorhabditis elegans shows that during embryogenesis endodermal cells interact with and regulate primordial germ cells by actively excising and digesting germ cell lobes. Endodermal cells utilize proteins linked to endocytosis to perform this unique 'cannibalistic' process.