OBJECTIVE Collagenous colitis (CC) and lymphocytic colitis (LC) are two subtypes of microscopic colitis (MC). Even though they most often are described as different entities they share many clinical and histological features. The aim of this study was to investigate the occurrence of conversion between CC and LC in a larger cohort of patients. MATERIALS AND METHODS All 664 patients in our Pat...

The aetiology of ulcerative colitis is unknown. Two patients without pre-existing inflammatory bowel disease in whom end colostomy for faecal incontinence was complicated by diversion colitis in the defunctioned rectosigmoid colon, are described. In both instances, colitis with the clinical, colonoscopic, and microscopic features of ulcerative colitis developed about a year later in the previou...

The aetiology of ulcerative colitis is unknown. Two patients without pre-existing inflammatory bowel disease in whom end colostomy for faecal incontinence was complicated by diversion colitis in the defunctioned rectosigmoid colon, are described. In both instances, colitis with the clinical, colonoscopic, and microscopic features of ulcerative colitis developed about a year later in the previou...

Microscopic colitis (MC) refers to chronic inflammation of the colon which is characterized by histologic changes at the level of a radiologically and endoscopically normal mucosa. It is a common cause of chronic non-bloody diarrhea that occurs primarily in older individuals; however, there are few studies in the literature with strong scientific evidence compared to other inflammatory bowel di...

REFERENCES 1 Ludvigsson JF, Bai JC, Biagi F, et al. BSG Coeliac Disease Guidelines Development Group; British Society of Gastroenterology. Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology. Gut 2014;63:1210–28. 2 Fitzgerald RC, di Pietro M, Ragunath K, et al., British Society of Gastroenterology. British Society of Gastroenterology guidel...

From the histologic point of view ‘colitis’ is microscopic inflammation of the colon. Colitis may be acute or chronic, diffuse or focal based on the etiological factor(s) and the type and distribution of the inflammatory infiltrate that prevails in the colon. Very often the pathologist encounters acute inflammation superimposed on chronic inflammation; this may be indicative of an acute exacerb...

EDITORIAL SYNOPSIS This study confirms the value of both the sigmoidoscopic assessment and the cytology of the mucosal secretion in the detection of microscopic disease of the rectal mucosa in ulcerative colitis. On certain occasions, however, microscopic disease is undetected using these methods, so that rectal biopsy is recommended as an aid in the diagnosis of patients with a history suggest...

Microscopic colitis, comprising collagenous colitis and lymphocytic colitis, is a common cause of chronic diarrhea. It is characterized clinically by chronic watery diarrhea and a macroscopically normal colonic mucosa where diagnostic histopathological features are seen on microscopic examination. The annual incidence of each disorder is 4-6/100,000 inhabitants, with a peak incidence in individ...

trinitrobenzene sulfonic acid (tnbs)-induced colitis is one of the most common methods for studying inflammatory bowel disease in animal models. several factors may, however, affect its reproducibility, rate of animal mortality, and macroscopic and histopathological outcomes. our aim was to validate the main contributing factors to this method and compare the effects of different reference drug...