the aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water/soluble drug, salbutamol sulphate by (water in oil) in oil emulsion technique using ethyl cellulose as the retardant material. various processing and formulation parameters such as drug/polymer ratio, stirring speed, volume of processing medium were optimized to maximize the e...

The aim of the present study was to prepare matrix pellets loaded nifedipine (NF) as model drug by pellitization technique by using blend of gelucire 50/13 (GL) and glyceryl palmito stearate (GPS) as hydrophilic and hydrophobic carriers in different concentrations. This system was able to prolong the drug release, minimizing the drug related adverse effects and improve bioavailability in differ...

The study was aimed isolate tamarind seed polysaccharide from tamarind kernel powder, crosslinking of isolated polysaccharide with epichlorohydrin and to assess the release behaviour of drugs, diclofenac sodium and ketoprofen from isolated tamarind seed polysaccharide and cross linked tamarind seed polysaccharide as release retardant. The presence of polysaccharide was confirmed by phytochemica...

Formulations of poorly aqueous soluble drugs in different polymers based on solid dispersion method have been used to improve its solubility and drug bioavailability. The aim this study was formulate albendazole utilising cellulose obtained from saccharum officinarum pseudostem bagasse characterised. Herein, a 32 factorial design factor out 9 combinations the generated (GC) lactose. In each cas...

The present investigation was focused to formulate semi-solid capsules (SSCs) of hydrophobic drug telmisartan (TLMS) by encapsulating semi-solid matrix of its solid dispersion (SD) in HPMC capsules. The combinational approach was used to reduce the lag time in drug release and improvise its dissolution. SDs of TLMS was prepared using hot fusion method by varying the combinations of Pluronic-F68...

The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water/soluble drug, salbutamol sulphate by (water in oil) in oil emulsion technique using ethyl cellulose as the retardant material. Various processing and formulation parameters such as drug/polymer ratio, stirring speed, volume of processing medium were optimized to maximize the e...

Objective: The main objective of the present study was to develop a controlled release formulation proniosomes thiocolchicoside. Methods: formulations were prepared with thiocolchicoside varying Span 60 and cholesterol ratio in range 4.5:1–1:4.5 using sucrose stearate as carrier by slurry method. different proniosomal characterized for micromeritic properties further %Entrapment efficiency, %Dr...