Trends in prevalence rates of onchocercal ocular lesions were examined over the period 1980 to 1990 using data from two cross-sectional surveys. There was evidence for increasing prevalence of anterior chamber microfilariae, iridocyclitis, optic atrophy, and chorioretinopathy. Large increases in prevalence, in particular, were seen for posterior segment lesions: optic atrophy increased from 2.7...

In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration sh...

A 50-year-old man presented with pedal edema and episodes of hematuria that had started 1 month before. Systemic examination revealed mild pedal edema and petechial rashes on both lower limbs, without lymphadenopathy. The urine color was noted to be milky white (Figure 1). Urine analysis showed 3þ albumin and numerous red blood cells. Urine spot protein creatinine ratio (PCR) was 14.8. Serum al...

NATARAJAN, P. N., ZAMAN V. & YEOH T. S. 1973. In vitro activity of diethylcarbamazine on the infective larvae, microfilariae and adult worms of Breinlia sergenti. International Journal for Parasitology. 3: 803-807. The action of diethylcarbamazine, on the infective larvae, the microfilariae and the adult worms of Breinlia sergenti, occurring in slow loris (Nycticebus coucang) is described. The ...

A Cameroonian affected with massive Loa loa infection developed febrile arthritis with involvement of both knees and the left ankle. Although the patient was first seen by us after one month of treatment with Indomethacin, at this time the joints were still inflamed and microfilariae of Loa loa were found in the synovial fluid. No other etiological mechanism was identified. Following the articu...

A case of loiasis diagnosed at Wankie Colliery Hospital is presented. The disease was suspected by the history of the patient and the presenting clinical signs, and it was confirmed by identification of Microfilariae loa loa in peripheral blood. The patient was successfully treated with a course of diethylcarbamazine. The paper gives a brief account of the clinical aspects of loiasis and emphas...

Microfilariae of Onchocerca volvulus from Guatemala were examined by scanning electron microscope. There are numerous transverse striations on the cuticular surface. The number of annulations varies from 325 to 357. The anterior end forms a round cephalic cap which bears a V-shaped hook. Two small openings are present on the cephalic cap. They are probably the openings of one of the amphidial c...

Microfilarial periodicity of Dirofilaria immitis (the dog heartworm) was determined at two hr intervals for 72 consecutive hrs in 10 naturally infected war dogs, 3-9 years old, in Korea to facilitate harvest of the microfilariae for possible use in laboratory works and to elucidate further the periodicity of the microfilaria depending on geographic location. Although the periodicity had been ob...

To determine the rate of appearance of new nodules during a specified period, a follow-up study on onchocercomas that had been removed was carried out in San Vicente Pacaya, Guatemala, between June 1976 and April 1977. Incidence rate, or rate of nodules appearing in initially negative subjects, was studied in relation to the degree of endemicity. Rates in a period of 7—8months in high, medium...

He pointed out the coincidence of the time of biting of the mosquito Culex jatigans, with that of the crowding of the filarial embryos in the peripheral circulation. McKenzie (1881) was able to demonstrate the reversibility of the periodicity of the microfilariae by reversing the sleeping and the waking habits of the infected human host. He also noted the coincidence of the biting hours of the ...