Olanzapine (OLN), an antipsychotic drug, is one of the most widely studied pharmaceutical materials. Although OLN and their multicomponent solids are highly crystalline, some molecular salts difficult to crystallize optimization takes a long time. After several batches failed crystallization, we applied mechanochemistry microcrystal electron diffraction (MicroED) for structure elucidation. This...

This paper describes structural elucidation of a layered conductive metal-organic framework (MOF) material Cu3(C6O6)2 by microcrystal electron diffraction with sub-angstrom precision. insight enables the first identification an unusual π-stacking interaction in MOF characterized extremely short (2.73 Å) close packing ligand arising from pancake bonding and ordered water clusters within pores. B...