Diabetic retinopathy (DR) has been reported to associate with gut microbiota alterations in murine models and thus “gut-retina-axis” proposed. However, the role of microbiome associated metabolism DR patients still need be elucidated. In this study, we collected fecal samples from 45 proliferative diabetic (PDR) 90 matched (1:2 according age, sex, duration diabetes) without (NDR) performed 16S ...

Abstract The stomach is inhabited by diverse microbial communities, co-existing in a dynamic balance. Long-term use of drugs such as proton pump inhibitors (PPIs), or bacterial infection Helicobacter pylori , cause significant alterations. Yet, studies revealing how the commensal bacteria re-organize, due to these perturbations gastric environment, are early phase and rely principally on linear...

This study investigated the effects of accidental contamination soils with phenol, toluene, nitric acid, and hydrogen fluoride (HF) by simulating chemical leakage in soil with/without rain characterizing resulting metabolites microbial. In case acid leakage, pH cation exchange capacity were decreased, content ion was increased HF leakage. Using mass spectrometry-based metabolomics analysis, phy...