The heavy-ion microbeam is used for targeted irradiation of living cells (in culture) with ions from the UNILAC linear accelerator of GSI [1]. A custom-made epifluorescence microscope is available for beam targeting as well as for observation of proteins (tagged by fluorescent dyes) in sub-compartments of interest. In order to gain better insight into DNA damage repair processes, we intend to e...

It is generally accepted and broadly recognized that one of the principal techniques for studying protein structures is synchrotron radiation diffraction. There are, however, many other areas in the field of nanobiosciences which increasingly make use of sophisticated synchrotron radiation techniques such as microbeam diffraction. The meeting on Synchrotron Radiation and Nanobiosciences covered...

In this paper static and dynamic responses of a fixed-fixed microbeam to electrostatic force and mechanical shock for different cases have been studied. The governing equations whose solution holds the answer to all our questions about the mechanical behavior is the nonlinear elasto-electrostatic equations. Due to the nonlinearity and complexity of the derived equations analytical solution are ...

In this paper, the vibration of microbeams due to a temperature pulse has been investigated. The thermoelastic coupled equations for microbeam resonator have been derived via the modified theory of couple stress in connection with the generalized thermoelasticity with relaxation time. The analytical expressions for studied fields due to modified couple stress for the microbeam have been obtaine...

Modified couple stress theory is applied to study of temperature effects on free vibration of Timoshenko functionally graded microbeams. Due to the interatomic and microstructural reactions of the structures in micro scale, the dynamic behavior of the microbeam is predicted more accurate applying the couple stress theory. Both of the simply supported and clamped boundary conditions are assumed ...

In this paper, the oscillations of an actuated, simply supported microbeam are studied for which it is assumed that electric load composed a small DC polarization voltage and small, harmonic AC voltage. Bending stiffness mid-plane stretching taken into account as well viscous or structural damping. No tensile axial force to be present. By using multiple time-scales perturbation method, approxim...

In this work, an analysis of thermoelastic, homogeneous, and isotropic microbeams was conducted in the context non-Fourier heat conduction law. The first end microbeam based on a graphene strip, which connected to electrical voltage source. Under simple boundary conditions maintained by fixed side ratios, Lord–Shulman model generalized thermoelasticity applied. thermally loaded with source due ...

Within the first few microseconds following a charged particle traversal of a cell, numerous oxygen and nitrogen radicals are formed along the track. Presented here is a method, using capillary electrophoresis, for simultaneous measurement, within an individual cell, of specific reactive oxygen species, such as the superoxide radical ([Formula: see text]) as well as the native and oxidised form...

PURPOSE There is now no doubt that bystander signalling from irradiated cells occurs and causes a variety of responses in cells not targeted by the ionizing track. However, the mechanisms underlying these processes are unknown and the relevance to radiotherapy and risk assessment remains controversial. Previous research by our laboratory has shown bystander effects in a human keratinocyte cell ...