Previous studies suggested that both the frequency and the mean fluorescence intensity (MFI) of cytokine secreting T cells could be of great value for immunogenicity evaluation of a vaccine. In this study, by constructing epitope-based DNA vaccines encoding a previously identified CD8(+) T cell epitope, we investigated the influence of multiplying epitope copies on both the frequency and the MF...

BACKGROUND Fatigue often occurs as long-term complication in chronically critically ill (CCI) patients after prolonged intensive care treatment. The Multidimensional Fatigue Inventory (MFI-20) has been established as valid instrument to measure fatigue in a wide range of medical illnesses. Regarding the measurement of fatigue in CCI patients, the psychometric properties of the MFI-20 have not b...

OBJECTIVES The purpose of this study was to monitor the effects of chimeric 7E3 Fab (ReoPro) on leukocyte and platelet activation and interaction during coronary angioplasty. BACKGROUND Increased expression of CD11b on monocytes and neutrophils promotes their adhesion to endothelial cells, extracellular matrix and smooth muscle cells. Thrombin-activated platelets adhere via P-selectin to mono...

Purpose: To compare the postoperative course of elderly patients (≥70 years) submitted to minimally-invasive(MIDP) vs. open distal pancreatectomy(ODP), and evaluate if modified Frailty Index (mFI) predicts surgical course. Methods: Data 204 aged ≥70 who underwent DP at single institution between March 2011 December 2019 were retrospectively retrieved. Of these patients, 42 MIDP propensity-score...

MFI type zeolite membranes were synthesized on two types of supporting materials, alumina (α-alumina) and yttria-stabilized zirconia (YSZ) coated alumina. Membranes were prepared by template-free secondary growth method with multiple growth steps in order to minimize intercrystalline gaps. Gas permeation characteristics, thermal and hydrothermal stability for MFI type zeolite membranes were exa...

BACKGROUND Many papers have focused on the importance of granulocytes in the process of reperfusion and ischemia. Most of the clinical studies measured several parameters of this process during and after coronary angiography, without taking into account the effect of the radiographic contrast media (RCM) used during this procedure. MATERIALS AND METHODS We performed a randomized patient study...

Hydrodeoxygenation of guaiacol in the presence of 1-octanol was studied in a fixed-bed reactor under mild conditions (50–250 °C) over platinum particles supported on silica (Pt/SiO2) and a zeolite with framework type MFI at a Si/Al-ratio of 45 (Pt/H-MFI-90). The deoxygenation selectivity strongly depended on the support and the temperature. Both guaiacol and octanol were rapidly deoxygenated in...

the number of couples seeking consultation for infertility problems has steadily increased over the past decade, affecting 10%-15% of the sexually active population. abnormal semen production, a male factor infertility (mfi), is thought to be the cause of up to 50% of all infertilities in developed countries. there are potentially many different causes of male infertility, including hormonal, a...

Devices which can obtain comparable bilaterally symmetrical acupoints (BSA) multifrequency impedances (MFI) are often needed in the detection of the energy balance states of acupoints in traditional Chinese medicine. To satisfy these needs, a two-channel impedance measurement system has been introduced which is capable of accurately and simultaneously measuring BSA MFI. The system includes a se...

OBJECTIVE To investigate whether CD40L/CD154 on platelets and soluble CD40L/CD154 may play a role in the inflammatory process of acute coronary syndromes. DESIGN AND SETTING Observational study in a university hospital. PATIENTS 15 patients with acute myocardial infarction, 25 patients with unstable angina, 15 patients with stable angina, and 12 controls. MAIN OUTCOME MEASURES CD40L/CD154...