نتایج جستجو برای: methyl ester
تعداد نتایج: 130453 فیلتر نتایج به سال:
UNLABELLED Cyclooxygenase (COX)-1 and -2 are prostanoid-synthesizing enzymes that play important roles in the regulation of neuroinflammation and in the development of neurodegenerative disorders. However, the specific functions of these isoforms are still unclear. We recently developed (11)C-labeled ketoprofen methyl ester as a PET probe that targets the COXs for imaging neuroinflammation, tho...
During the second hour after giving 100 ,ug of orally administered prostaglandin 15 (R) 15-methyl-E, methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid secretion took place. At this dose no excessive uterine stimulation was observed. Prostaglandin 15 (R) 15-methyl-E, methyl ester could prove of value in the preoperative preparation of the pregnant patient ...
Synthesis, characterization and antimicrobial studies of Sb(III) complexes of substituted thioimines
Some antimony complexes of a new class of substituted thioimines have been prepared by reacting Ph3Sb (III) with [1-(2-naphthyl) ethyledene] hydrazinecarbodithioic acid phenyl methyl ester (LH), [1-(2-thienyl) ethyledene] hydrazinecarbodithioic acid phenyl methyl ester (LH), [1-(2-pyridine) ethyledene] hydrazinecarbodithioic acid phenyl methyl ester (LH) and [1-(2-furanyl)ethyledene] hydrazinec...
1. Glutamate dehydrogenase was inhibited by l-serine O-sulphate, beta-chloro-l-alanine, O-phospho-l-serine and beta-chloro-l-alanine methyl ester. With the exception of beta-chloro-l-alanine methyl ester which was an irreversible inhibitor, it was possible to reverse the inhibitory effects by dialysis. 2. Both NAD(+) and glutamate afford some protection against the inhibition due to the methyl ...
An earlier proposed endoperoxide intermediate in the biosynthesis of prostaglandins was detected in short-time incubations of arachidonic acid with the microsomal fraction of homogenates of sheep vesicular glands. Conversion of the endoperoxide into prostaglandin E(2) was stimulated by reduced glutathione but suppressed by p-mercuribenzoate and N-ethylmaleimide. The methyl ester of an unknown c...
We have isolated glutamic acid 5-methyl ester from an Escherichia coli protein that is involved in chemotaxis. The bacteria were first incubated with [methyl-“Hlmethionine under conditions which are known to result in methylation of the protein. The protein, isolated by gel electrophoresis, was then digested by successive treatment with three proteolytic enzymes. One of the products was [methyl...
This work was to find out the dominant secondary metabolites derived from the fungus Trichoderma and to test them against skin cancer protein. The metabolites were extracted in 80% methanol from the fungal biomass of Trichoderma isolated from mangrove sediment. The crude methanol extract was purified and analysed for the secondary metabolites by GC-MS. Three predominant compounds (heptadecanoic...
This study evaluated the feasibility of using methyl ester prepared from waste cooking oil for electrical insulation in distribution transformers. Methyl is produced by a transesterification reaction between and methanol sodium hydroxide as catalyst. The physicochemical parameters breakdown voltage were determined. effects ageing on voltage, viscosity acid value also investigated. In addition, ...
A series of linear and macrocyclic peptides 3-12 were synthesized using 3,5-pyridinedicarboxylic acid (1) as starting material and screened for their antimicrobial, anti-inflammatory and anticancer activities. Bis-ester 3 was prepared from 1 and L-leucine methyl ester. Hydrazinolysis and hydrolysis of dipeptide methyl ester 3 with hydrazine hydrate or 1 N sodium hydroxide afforded compounds 4 a...
Herein, we report the crystal structure of 2,7-dichlorofluorescein methyl ester (DCF-ME) and its fluorescence response to hydroxyapatite binding. The reported fluorophore is very selective for staining bone matrix and...
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