The diuretic potential of methanolic extract of whole plant of Jussiaea suffruticosa was evaluated in male albino rats. The volume of urine, urinary concentration of sodium, potassium and chloride ions was the tested parameters of the study. Furosemide (100 mg/kg) was used as standard. Methanolic extract was tested in dose levels of 200 and 400 mg/kg. The methanolic extract at 400 mg/kg dose le...

In vitro antioxidant activities of methanolic extract of tuberous root of coleous vettiveroides (jacob.) was investigated. The free radical scavenging activity to evaluate by DPPH (2,2 -diphenyl -1picryl hydrazyl) method, Nitric oxide method, Total antioxidant activity. DPPH radical scavenging activity of Methanolic extract and reference standard Rutin IC50 values was found to be 250 μg/ml and ...

Methanolic and ethyl acetate extract of A. galanga showed significant central nervous system (CNS) stimulant activity in mice using actophotometer and rotarod test. CNS stimulation at a dose of 500 mg/kg was comparable with standard drugs caffeine and amphetamine derivative modalart. The extracts did not shown any depressant effect in forced swim or tail suspension tests. It can be concluded th...

Oral administration (200 mg/kg) of Foeniculum vulgare fruit methanolic extract exhibited inhibitory effects against acute and subacute inflammatory diseases and type IV allergic reactions and showed a central analgesic effect. Moreover, it significantly increased the plasma superoxide dismutase (SOD) and catalase activities and the high density lipoprotein-cholesterol level. On the contrary, th...

Melilotus indicus (Linn.) All. is a small herb distributed throughout Pakistan and has a number of ethnomedicinal uses. It is also consumed as a vegetable. In the present work, we are reporting the alpha-amylase and urease inhibitory activities of methanolic extract of M. indicus and its sub-fractions in different solvents. Both the methanolic extract and its fractions in chloroform, ethyl acet...

Objective: The present study was designed to investigate the antiarthritic activity of methanolic stem extract of Tecoma stans in wistar albino rats using in vitro albumin denaturation method and in vivo models like complete freunds adjuvant (CFA) induced arthritis and egg albumin induced arthritic models. Acute toxicity studies were carried out and the extract was found to be safe upto 2000 mg...

Miconia is one of the largest genus of the Melastomataceae, with approximately 1,000 species. Studies aiming to describe the diverse biological activities of the Miconia species have shown promising results, such as analgesic, antimicrobial and trypanocidal properties. M. albicans leaves were dried, powdered and extracted to afford chloroformic and methanolic extracts. Total phenolic contents i...

In the present study, we evaluate the analgesic activity of methanolic extract obtained from Jatropha unicostata balf leaves, using chemical and thermal models which will induce acute pain in mice and rats. This study was carried out by using sex Swiss mice (20-30gm) and wistar male rats (200-250gm).The methanolic extract was prepared by using maceration at room temperature (25°) over the perio...

Abstract: A methanol extract of the roots of Stemona tuberosa (Stemonaceae) significantly inhibited lipopolysaccharide-induced nitric oxide production in murine BV2 microglial cells. Eight alkaloids tuberostemonine K (1), neotuberostemonine (2), oxotuberostemonine (3), bisdehydroneotuberostemonine (4), epibisdehydrotuberostemonine J (5), bisdehydrotuberostemonine (6), tuberostemoninol (7), and ...

Some medicinal plants are used traditionally in Saudi Arabia to treat many bacterial infections. Three plants, lemongrass (Oymbopogon citrates), lantana (Lantana camara), and wild olive leaves (Olea europaea) were collected, identified, extracted with either hot water or organic solvents (methanol, diethyl ether, ethyl acetate and n-butanol) to investigate their antibacterial activities against...