Bioinorganic medicinal chemistry remains a hot field for research aimed at developing novel anti-cancer treatments. Discovery of metal complexes as potent antitumor chemotherapeutics such as cisplatin led to a significant shift of focus toward organometallic/ bioinorganic compounds containing transition metals and their chelates as novel scaffolds for drug discovery. In that way, transition met...

We measured in a comet assay the damage of DNA in the hemocytes of various stages of the grasshopper Schistocerca gregaria after exposing them to various doses of Cd and Pb in the food. The mechanisms of Cd and Pb toxicity for grasshopper are discussed. The accumulation of heavy metals and stage of the insect may play important roles in causing the DNA damage. S. gregaria may be considered a va...

Recent advances in digestion methods used in the analysis of precious metal samples by spectrometric techniques are reviewed. The applicability of a fire assay, a wet acid treatment, chlorination and alkaline oxidizing fusion to a quantitative recovery of metals from various materials is discussed. Data on the precious metal contents obtained by using particular digestion methods as well as UV-...

The accurate and precise determination of gold and other precious metals (PMs) is a vital task for companies involved in PM production and the contract or service laboratories that support them. This might involve the processing of hundreds of samples typical of exploration and mining activities, or supplying the quality control assay of the fi nal product from PM producers or recyclers. PMs ar...

The application of activation techniques to the assay of the refractory metals niobium, molybdenum, tantalum and tunjsten for their trace element impurities is reviewed. Activation with reactor neutrons, fast neutrons, charged partides and photons in connection with both the non-destructive and the radiochemical performance is considered. The decisive contribution of activation techniques to th...

OBJECTIVES Chronic low-level metal exposure may result in metal sensitization and undesirable side-effects. The main sources of metal exposure are from the environment or from corrosion of dental metal alloys. Affected patients are routinely diagnosed with the epicutaneous (patch) test. However, such testing may induce false-positive (irritative) reactions and may in itself sensitize or exacerb...

BACKGROUND Polygonum hydropiper L decoctions are traditionally used in the treatment of various ailments including inflammation, dyspepsia, diarrhea, menorrhagia, hemorrhoids, helminthiasis and CNS disorders. Present study was undertaken to investigate P. hydropiper L. for heavy metals content, phytoconstituents, Phytotoxic and anthelmintic activities to explore its toxicological and pharmacolo...

Currently, heavy metals pollution is significantly becoming a global concern as it causes severe toxicity towards human health and the environmental condition. Intensive efforts to develop highly sensitive, rapid, simple assay assess toxic effects of in aquatic bodies have been done. An emerging tool solve this matter by using microorganisms one them yeast. In study, simple, cost-efficient Bake...