Studies in model organisms have identified regulatory processes that profoundly influence aging, many of which modulate resistance against environmental or metabolic stresses. In Caenorhabditis elegans, the transcription regulator SKN-1 is important for oxidative stress resistance and acts in multiple longevity pathways. SKN-1 is the ortholog of mammalian Nrf proteins, which induce Phase 2 deto...

Femtosecond pump-probe absorption spectroscopy in tetrahydrofuran solution has been used to investigate the dynamics of a metalloid cluster compound {Ge9[Si(SiMe3)3]3}(-). Upon UV photoexcitation, the transients in the near-infrared spectral region showed signatures reminiscent of excess electrons in THF (bound or quasi-free) whereas in the visible part excited state dynamics of the cluster com...

Amorphous (Zr,Hf)37Si63 alloys were produced by sputtering. Their total structure factors were determined by X-ray diffraction. Using the methods of isomorphous substitution and Reverse Monte Carlo simulation, the partial pair correlation functions were obtained. The results were compared with the partial functions of amorphous Ti40Si60. In the amorphous alloys under investigation the transitio...

This review focuses on the therapeutic effects of ions when released in physiological environments. Recent studies have shown that metallic like Ag+, Sr2+, Mg2+, Mn2+, Cu2+, Ca2+, P+5, etc., promising results drug delivery systems and regenerative medicine. These can be loaded nanoparticles, mesoporous bioactive glass nanoparticles (MBGNs), hydroxyapatite (HA), calcium phosphates, polymeric coa...

Three centipede species (Clinopodes flavidus, Cryptops anomalans and Eupolybothrus transsylvanicus) were used as bioindicators of trace metal metalloid pollution in Belgrade, Serbia. The concentrations 13 elements (the metals Mn, Co, Ni, Cu, Zn, Rb, Sr, Cd, Tl, Pb U metalloids As, Se) whole animals soil measured by inductively coupled plasma mass spectrometry (ICP-MS). Differences the some anal...

Parasites and pollutants can both affect any living organism, and their interactions can be very important. To date, repeated studies have found that parasites and heavy metals or metalloids both have important negative effects on the health of animals, often in a synergistic manner. Here, we show for the first time that parasites can increase host resistance to metalloid arsenic, focusing on a...

This paper summarizes our studies on metal and metalloid uptake by the date palm, Phoenix dactylifera L., a tree of considerable importance in arid regions. The typical concentrations of 17 elements in the date palm are summarized and compared with existing data in the scientific literature. The role and toxicity of these elements are considered. Issues encountered by us during sample collectio...