نتایج جستجو برای: metabolic profiling
تعداد نتایج: 296594 فیلتر نتایج به سال:
The term metabolic profiling is often used to denote the systematic characterization of the unique biochemical trails or fingerprints left behind by cellular processes. Advances in computational biosciences are often invaluable in dealing with the huge amount of raw data generated from the countless biochemical intermediates that flood the cell at any given time. As a prelude to metabolic profi...
metabolomics studies provide useful information about health and disease status. metabolite based investigations on various cancers is a powerful approach to diagnosis, prognosis and therapy of cancer diseases. recently by using advanced analytical techniques such as nmr and ms and its hyphenation methods, global metabolic profiling of diseases has been possible. it is predictable that internat...
Metabolic profiling in liver and serum of mice was studied for the combined toxic effects of deoxynivalenol (DON) and zearalenone (ZEN), through gas chromatography mass spectrum. The spectrum of serum and liver sample of mice, treated with individual 2 mg/kg DON, 20 mg/kg ZEN, and the combined DON + ZEN with final concentration 2 mg/kg DON and 20 mg/kg ZEN for 21 days, were deconvoluted, aligne...
Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells.
Rational engineering of complicated metabolic networks involved in the production of biologically active plant compounds has been greatly impeded by our poor understanding of the regulatory and metabolic pathways underlying the biosynthesis of these compounds. Whereas comprehensive genome-wide functional genomics approaches can be successfully applied to analyze a select number of model plants,...
Pantothenate kinase-associated neurodegeneration (PKAN) is a rare, inborn error of metabolism characterized by iron accumulation in the basal ganglia and by the presence of dystonia, dysarthria, and retinal degeneration. Mutations in pantothenate kinase 2 (PANK2), the rate-limiting enzyme in mitochondrial coenzyme A biosynthesis, represent the most common genetic cause of this disorder. How mut...
The post-genomic era is characterized by a range of high throughput profiling methods capable broadly characterizing gene expression levels, protein, and metabolite abundances. Application these methods, enzyme profiling, more recently, protein-metabolite interactions flux analysis have alongside modeling approaches allowed us to refine our understanding the regulation metabolism even in case c...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید