نتایج جستجو برای: metabolic engineering
تعداد نتایج: 476262 فیلتر نتایج به سال:
Engineering metabolites in microorganisms are new tools for production of therapeutics. Microbial metabolic engineering involving manipulation of metabolic fluxes has helped in the production of novel antibiotics. The process of metabolic engineering and strategies adopted for over production of antibiotics, enzymes of therapeutical value and other therapeutic compounds are briefly described he...
Evolutionary engineering of Saccharomyces cerevisiae for improved industrially important properties.
This article reviews evolutionary engineering of Saccharomyces cerevisiae. Following a brief introduction to the 'rational' metabolic engineering approach and its limitations such as extensive genetic and metabolic information requirement on the organism of interest, complexity of cellular physiological responses, and difficulties of cloning in industrial strains, evolutionary engineering is di...
Title of Document: A SYSTEMS ENGINEERING FRAMEWORK FOR METABOLIC ENGINEERING EXPERIMENTS Joseph Johnnie, Master of Science in Systems Engineering, 2011 Directed By: Dr. Mark Austin, Department of Civil and Environmental Engineering, and the Institute for Systems Research, University of Maryland at College Park Cells of living organisms simultaneously operate hundreds or thousands of interconnec...
Title of Document: A SYSTEMS ENGINEERING FRAMEWORK FOR METABOLIC ENGINEERING EXPERIMENTS Joseph Johnnie, Master of Science in Systems Engineering, 2011 Directed By: Dr. Mark Austin, Department of Civil and Environmental Engineering, and the Institute for Systems Research, University of Maryland at College Park Cells of living organisms simultaneously operate hundreds or thousands of interconnec...
Today, vascular diseases such as atherosclerosis are one of the leading causes of death in the world and the prevalence of it in older societies is rising. The current treatments for repair of cardiovascular function include organ transplantation, surgical reconstruction, mechanical or artificial devices, or the use of metabolic products. Although these methods are commonly used, they did not g...
The traditional use of the yeast Saccharomyces cerevisiae in alcoholic fermentation has, over time, resulted in substantial accumulated knowledge concerning genetics, physiology, and biochemistry as well as genetic engineering and fermentation technologies. S. cerevisiae has become a platform organism for developing metabolic engineering strategies, methods, and tools. The current review discus...
Industrial biotechnology promises to revolutionize conventional chemical manufacturing in the years ahead, largely owing to the excellent progress in our ability to re-engineer cellular metabolism. However, most successes of metabolic engineering have been confined to over-producing natively synthesized metabolites in E. coli and S. cerevisiae. A major reason for this development has been the d...
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