Objective(s): Weight gain and metabolic disturbances such as dyslipidemia, are frequent side effects of second-generation antipsychotics, including olanzapine. This study examined the metabolic effects of chronic olanzapine exposure. In addition, we investigated the hepatic fatty acid effects of olanzapine in female C57BL/6J mice fed a normal diet.Materials and Methods: Female C57BL/6J mice ora...

objective: to ascertain the effects of soy [in the forms of textured soy protein (tsp) and soy-nut] on lipid profiles, apolipoproteins, inflammatory and prothrombotic markers and blood pressure in elderly women with the metabolic syndrome. materials and methods: the study is a 12-week parallel randomized controlled trial that was conducted in rural health centres of babol, iran. the participant...

alone and together, upon total heat production of normal rabbits, thryroidectomized rabbits, and thyroidectomized rabbits treated with thyroxin. Data so obtained were then supplemented with results of clinical studies, and from the whole, conclusions were drawn which are convincing, both because of the straightforward nature of the experiments themselves and the logical, orderly manner in which...

alone and together, upon total heat production of normal rabbits, thryroidectomized rabbits, and thyroidectomized rabbits treated with thyroxin. Data so obtained were then supplemented with results of clinical studies, and from the whole, conclusions were drawn which are convincing, both because of the straightforward nature of the experiments themselves and the logical, orderly manner in which...

The goal of this study was to test whether the "loss of the complexity" hypothesis can be applied to compare the metabolic patterns of mouse models with known differences in metabolic and endocrine function as well as life span. Here, we compare the complexity of locomotor activity and metabolic patterns (energy expenditure, VO₂, and respiratory quotient) of the long-lived growth hormone recept...

Introduction: Metabolic syndrome is defined as a cluster of metabolic disorders, which may lead to type II diabetes and cardiovascular diseases. Promotion of healthy lifestyle and use of herbal supplements with anthocyanin and phenols are recommended for the treatment of metabolic syndrome. The present study aimed to investigate the effects of eight weeks of combined aerobic an...

Background: -Fasting, the voluntary abstention from all restricted foods, is a feature of many religions, and the putative health benefits have attracted both scientific and popular interest. There is no clear understanding that religious fasting has great effects on metabolic syndrome. There is little data available that provides information concerning Ethiopian Orthodox Christians fasting inf...

Generalized linear mixed models(GLMMs) are frequently used for the analysis of longitudinal categorical data when the subject-specific effects is of interest. In GLMMs, the structure of the random effects covariance matrix is important for the estimation of fixed effects and to explain subject and time variations. The estimation of the matrix is not simple because of the high dimension and the ...