Chondrocytes are mesenchymally derived cells that reportedly acquire some epithelial characteristics; however, whether this is a progression through a mesenchymal to epithelial transition (MET) during chondrosarcoma development is still a matter of investigation. We observed that chondrosarcoma cells acquired the expression of four epithelial markers, E-cadherin,desmocollin 3, maspin, and 14-3-...

  Mesenchymal chondrosarcoma (MC) is an uncommon tumor with an aggressive behaviour. We present two cases of MC. The first one is a unique case of MC of the maxilla metastasized from the clavicle. The second describes MC in the mandible with extensive involvement of the condyle. A 31-year-old male and a 22-year-old male presented to Saveetha Dental College, with a 2-month history of progressiv...

Chondrosarcoma is a malignant tumor characterized by the proliferation of chondroblasts producing no bone , which can sometimes developed by metaplasia inside a connective tissue and present a rapid growth of both cartilaginous and connective tissues. Chondrosarcoma is a very rare tumor, two times less frequent than osteosarcoma. It may represent 11-20% of all malignant bone tumors as reported ...

Mesenchymal chondrosarcoma (MC) is an uncommon tumor with an aggressive behaviour. We present two cases of MC. The first one is a unique case of MC of the maxilla metastasized from the clavicle. The second describes MC in the mandible with extensive involvement of the condyle. A 31-year-old male and a 22-year-old male presented to Saveetha Dental College, with a 2-month history of progressive m...

Mesenchymal chondrosarcoma is a rare malignant tumor. It may exhibit as a skeletal or extraskeletal tumor and usually contains calcified deposits. A lesion arising from sacrum is extremely rare. We present a 17-year-old male patient with clinical manifestations of lower back pain and sciatica. Computed tomography and magnetic resonance images of the patient depicted a poorly demarcated sacral t...

Mesenchymal chondrosarcoma, a rare malignant tumor, was predominantly occurring in the bone and may involve somatic soft tissue but it is extremely rare in the lung.We report the case of a 20-year-old female who presented with a 2-month history of irritant nonproductive cough and chest pain. The histopathologic examination revealed the tumor composed of atypical undifferentiated small cells and...

Chondrosarcoma of the prostate is a rare variant of prostatic cancer. Tumors are most commonly composed of an admixture of both original mesenchymal cells and well-differentiated chondrocytes. It is a kind of highly malignant aggressive tumor, which is rich in blood vessels. A unique case of chondrosarcoma of the prostate detected in a 59-year-old man who underwent transurethral resection of th...

Mesenchymal chondrosarcoma is a rare disease with poor prognosis. Treatment including wide or radical excision is very important. Radiotherapy and chemotherapy are additional treatment options, but no conclusive results for their efficacy have been shown until date. Imaging modalities can give important clues for diagnosis and management planning. Angioembolization before surgery could be usefu...