We have investigated the effect of age on thoracic extradural dose requirements in 62 patients aged 20-79 yr. Fifteen millilitre of 2% mepivacaine was administered at a constant rate (1 ml s-1) by syringe pump through an extradural needle at the T9-10 interspace. A mean of 15.5 (SD 4.2) spinal segments were blocked 15 min after completion of the administration. The extradural dose requirement d...

PURPOSE To examine the effect of modifying the interval between administration of saline used during the loss of resistance (LOR) method and local anesthetic on epidural anesthetic level and its quality. METHODS Seventy-three patients who received thoracic epidural anesthesia were randomly allocated into three groups; the 2, 5 and 10 min groups, according to the interval between the administr...

The purpose of this study was evaluation of anesthesia success rate of 3% mepivacaine compared with 2% lidocaine 1/80000 epinephrine in inferior alveolar nerve block in thirty voluntary students. All of the subjects were healthy and had not received any medicament. They pariticipated for two appointments and each time randomly received an inferior alveolar nerve injection with one of the anesth...

Complement activation and anaphylatoxin formation were studied in 28 patients undergoing aortic reconstructive surgery under general anaesthesia. In 12 of the patients an extradural catheter was placed in the L1-2 space and 2% mepivacaine was injected until blockade reached the T4 level. The remaining 16 patients were operated upon under general anaesthesia alone. Complement activation was not ...

After IRB approval, we retrospectively reviewed the regional anesthesia database of one staff anesthesiologist (ERM) from a university hospital outpatient surgery center collected over one year as part of an ongoing quality assurance (QA) project. Data from patients who received perivascular AXB or coracoid ICB were included. Nerve blocks were performed preoperatively using sterile technique in...

A healthy woman developed neurological symptoms after two consecutive Caesarean sections under combined spinal and epidural anaesthesia. Amethocaine was used for spinal anaesthesia and mepivacaine for epidural anaesthesia on both occasions, and a combination of fentanyl and bupivacaine was continuously infused for pain relief after the second. Her symptoms on both occasions were similar, includ...