Thirty-seven patients with retinoblastoma were evaluated prospectively by clinical examination, lumbar puncture, and CT. Eight (22%) of the 37 were found to have meningeal dissemination. The tumor was bilateral in three patients. Two cases showed no CT signs of local recurrence. Headache, nauseajvomiting, and restlessness were the most common symptoms. CT scans in these patients showed diffuse ...

A case of malignant neoplasm is described in which the initial manifestations were mental dysfunction and meningeal irritation, mimicking chronic or subacute meningitis. Physical examination showed cranial nerve involvement and a pelvic tumor. There was progressive deterioration, and death occurred in 2 weeks. The autopsy revealed a gallbladder adenocarcinoma, meningeal carcinomatosis, and ovar...

OBJECTIVE To identify serotypes and susceptibility of S. pneumoniae strains from 48 children with invasive infections and 50 carriers. MATERIAL AND METHODS Typing was performed by the Quellung reaction and susceptibility by Kirby-Bauer and Etest according to CLSI standards. RESULTS Of 31 meningeal strains, serotypes 19F, 3, 6B, 14 and 23F were predominant. Resistance to penicillin and STX w...

Objective: It was previously reported that increasing serum level of glucagon-like peptide-2 (GLP-2) is a risk factor of migraine in human. The headache phase of a migraine attack is thought to originate in vasodilation of meningeal blood vessels followed by activation of the nociceptive trigeminal nerve innervating these vessels. However, it is unclear how GLP-2 acts on this pathway. In the pr...

Traumatic pseudoaneurysm of the middle meningeal artery is rare and is associated with high mortality. Skull fracture is usually an associated feature of this entity. An elderly male was brought to our hospital in a stage of coma. The details of ictus were not known. The Glasgow coma scale score was 9/15. Examination revealed a pseudo-aneurysm arising from the posterior branch o...

Objective: It was previously reported that increasing serum level of glucagon-like peptide-2 (GLP-2) is a risk factor of migraine in human. The headache phase of a migraine attack is thought to originate in vasodilation of meningeal blood vessels followed by activation of the nociceptive trigeminal nerve innervating these vessels. However, it is unclear how GLP-2 acts on this pathway. In the pr...

The meningeal worm (Parelaphostrongylus tenuis) is a nematode parasite that commonly infects white-tailed deer (Odocoileus virginianus; WTD) throughout the deciduous forest biome and deciduous-coniferous ecotone of eastern and central North America; the species is not known to occur west of the grassland biome of central North America. We used county-specific prevalence data to evaluate potenti...

BACKGROUND Meningeal and other trigeminal nociceptors are thought to play important roles in the initiation of migraine headache. Currently, the only approved peripherally administered chronic migraine prophylactic drug is onabotulinumtoxinA. The purpose of this study was to determine how botulinum neurotoxin type A (BoNT-A) affects naïve and sensitized meningeal nociceptors. MATERIAL AND MET...