G. Paun, E. Neagu, A. Tache, G. L. Radu, and V. Parvulescu National Institute for Research-Development of Biological Sciences – Centre of Bioanalysis, 296 Spl.Independentei, PO Box 17-16, 060031, Bucharest 6, Romania Politehnica University of Bucharest, Faculty of Applied Chemistry and Materials Science, 313 Spl.Independentei, 060042, Bucharest, Romania Institute of Physical Chemistry, Splaiul ...

The present study was carried out to evaluate the spermatotoxic effect of ochratoxin and it's amelioration by Emblica officinalis aqueous extract. When male albino mice were treated with ochratoxin (50 and 100 microg/0.2 mL of olive oil/animal/day for 45 days, orally) alterations in various reproductive parameters were observed (sperm count, sperm motility, sperm viability and fertility rate), ...

Due to the side effects of synthetic drugs, the therapeutic potential of natural products for Alzheimer's disease (AD) has gained interest. Morinda officinalis has demonstrated inhibitory effects on geriatric diseases, such as bone loss and osteoporosis. However, although AD is a geriatric disease, M. officinalis has not been evaluated in an AD bioassay. Therefore, M. officinalis extracts and f...

INTRODUCTION In cirrhosis some toxic substances accumulate in brain and modify the expression of several neuronal receptors. Thus, the use of medicinal plants such as Rosmarinus officinalis L. has been proposed in several pathologies due to its hepatoprotective, antioxidant and neuroprotective activity. In this study we evaluated the expression of the subunits NR1, NR2A and NR2B of the glutamat...

OBJECTIVE We aimed to assess the influence of Melissa officinalis (lemon balm), a well-known herbal drug with numerous applications in traditional and modern medicine, on cardiac conduction and susceptibility to lethal ventricular arrhythmia. MATERIALS AND METHODS Forty-two male Wistar rats were divided into a control group (CTL), an M. officinalis group that received the aqueous extract of M...

The Uygur herb, Hyssopus officinalis L., has been demonstrated to affect the levels of a number of cytokines in asthmatic mice, including interleukin-4, -6 and -17 and interferon-γ. In the present study, the effect of Hyssopus officinalis L. on airway immune regulation and airway inflammation was investigated in a mouse model of chronic asthma. A total of 32 BALB/c mice were randomly divided in...

Oryza officinalis has proven to be a natural gene reservoir for the improvement of domesticated rice as it carries many desirable traits; however, the transfer of elite genes to cultivated rice by conventional hybridization has been a challenge for rice breeders. In this study, the conserved sequence of plant stress-related NAC transcription factors was selected as a probe to screen the O. offi...

Melissa officinalis L. is a medicinal plant with a large variety of pharmacological effects and traditional applications. This study aimed to evaluate the protective and antioxidant activities of the extract of M. officinalis aerial parts on human umbilical vein endothelial cells (HUVECs) under oxidative stress induced by H2O2. Cells were incubated with H2O2 (0.5 mM, 2 h) after pretreatment wit...

BACKGROUND Several studies are conducted on Premenstrual Syndrome (PMS). However, a few herbal surveys exist on the treatment of PMS in Iran. Due to the sedative effects of Melissa officinalis (M. officinalis), this question comes to mind that "can it be used in the treatment of PMS symptoms?" OBJECTIVES The current study aimed to assess the effect of M. officinalis capsule on the intensity o...

Fumaria officinalis is one of the herbal medicines used in Iran extensively. There are many useful properties recognized for this plant, but there is no information about its side effects especially in long term and at high doses. The objective of the present study was to investigate the effects of F. officinalis hydroalcoholic extract on the Blood Urea Nitrogen (BUN) and serum creatinine conce...