The Drosophila MEI-S332 protein has been shown to be required for the maintenance of sister-chromatid cohesion in male and female meiosis. The protein localizes to the centromeres during male meiosis when the sister chromatids are attached, and it is no longer detectable after they separate. Drosophila melanogaster male meiosis is atypical in several respects, making it important to define MEI-...

To inquire whether the loci identified by recombination-defective and disjunction-defective meiotic mutants in Drosophila are also utilized during mitotic cell division, the effects of 18 meiotic mutants (representing 13 loci) on mitotic chromosome stability have been examined genetically. To do this, meiotic-mutant-bearing flies heterozygous for recessive somatic cell markers were examined for...

Measured Equation of Invariance(MEI) is a new concept in computational electromagnetics. It has been demonstrated that the MEI is such an eecient boundary truncation technique that the meshes can be terminated very close to the object and still strictly preserves the sparsity of the FD equations. Therefore, the nal system matrix encountered by MEI is a sparse matrix with size similar to that of...

In an effort to isolate novel meiotic mutants that are severely defective in chromosome segregation and/or exchange, we employed a germline clone screen of the X chromosome of Drosophila melanogaster. We screened over 120,000 EMS-mutagenized chromosomes and isolated 19 mutants, which comprised nine complementation groups. Four of these complementation groups mapped to known meiotic genes, inclu...

Katanin is a heterodimeric microtubule-severing protein that is conserved among eukaryotes. Loss-of-function mutations in the Caenorhabditis elegans katanin catalytic subunit, MEI-1, cause specific defects in female meiotic spindles. To determine the relationship between katanin's microtubule-severing activity and its role in meiotic spindle formation, we analyzed the MEI-1(A338S) mutant. Unlik...

During Mei-Yu season of Taiwan (May-June), fronts often pass through Taiwan region and interact with the large-scale circulation and land-sea breezes which would also affect the diurnal cycle of wind field and precipitation. This study divides the Mei-Yu season of 2008-2012 into pre-Mei-Yu (5/15-5/31), mid-Mei-Yu (6/1-6/15), post-Mei-Yu (6/166/30) in order to discuss the seasonal changes of the...

BACKGROUND Regular physical activity (PA) provides health benefits; however, at least 60% of the population fails to engage in the recommended amount of PA required to produce these health benefits. PURPOSE The primary purpose of the study was to examine over a 12-week structured exercise program the effect of a multifaceted efficacy intervention (MEI-i.e., task and specific types of self-reg...

In Exp. 1, six individually fed Hereford steers were exposed to hot (HOT) or thermoneutral (TNL) environmental conditions (ENV) while being adapted (stepped-up) to a finishing diet by decreasing roughage level from 55 to 10% of the diet DM over 17 d. Only at 10% roughage did heat exposure result in reduced (P<0.05) calculated ME intake (MEI) and measured DMI. In the TNL treatment group, pulse r...

In the Drosophila ovary, bone morphogenetic protein (BMP) ligands maintain germline stem cells (GSCs) in an undifferentiated state. The activation of the BMP pathway within GSCs results in the transcriptional repression of the differentiation factor bag of marbles (bam). The Nanos-Pumilio translational repressor complex and the miRNA pathway also help to promote GSC self-renewal. How the activi...