this case report states a 25-year-old woman, residing in the city of dezfool, khuzestan province, south of iran with the diagnosis of cutaneous leishmaniasis in june 2008. her skin lesion had de­veloped from 8 months earlier as a nodule on her left arm, 1×3 cm in diameter. because of sever­ity of the lesion, we prescribed meglumine antimoniate intralesionally with giving up her breast feeding. ...

A comparison of an indirect immunofluorescence test using promastigotes (IFATp) or cultured amastigotes (IFATa) in the diagnosis and follow-up of canine leishmaniasis caused by Leishmania infantum was carried out. Results obtained with both diagnostic methods were in good agreement although the IFATa titration was more sensitive than the currently used IFATp without losing specificity. The high...

INTRODUCTION Visceral leishmaniasis is a public health problem, with lethality reaching 10%. The recommended drug treatment is methylglucamine antimoniate. This study aimed to evaluate drug use for cases of visceral leishmaniasis treated at the Infectology Clinic of the Campo Grande University Hospital Center, State of Mato Grosso do Sul. METHODS To collect data, we examined the medical recor...

This study evaluated the in vitro sensitivity of paired Leishmania braziliensis samples isolated from the same patient before pentavalent antimonial treatment (Sample A) and after treatment failure or cutaneous leishmaniasis reactivation (Sample B) in patients undergoing intralesional administration or injections (5 mgSb(V)/kg/d) of meglumine antimoniate. Fourteen samples from 7 patients were s...

We aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical trials and observational studies that assessed the pharmacological treatment of the following groups of patien...

Cutaneous Leishmaniasis (CL) is a skin infection caused by various species of Leishmania parasites, which is transmitted by infected Phlebotomus sandfly bites. Pentavalent antimonials (meglumine antimoniate and sodium stibogluconate) are used for the treatment of adult CL patients as an effective and safe method. Liposomal amphotericin B is an alternative for the treatment of choice in cutaneou...

background: successful therapy of leishmaniasis depends on effective cellular immune response. we evaluated the effectiveness of sodium selenite and zinc sulphate as known immunomodulator materials, in combination with glucantime® in treatment of cutaneous leishmaniasis lesions resulting from leishmania ma­jor in susceptible animal model. methods: thirty three female mice weighing 18-20 g at th...