Thyroid cancers are especially common in patients who have received irradiation to the head and neck region for benign diseases. Well-differentiated papillary and/or follicular carcinomas are the most common types of thyroid cancer. They grow slowly and have a very good prognosis when managed with an appropriate combination of surgical and medical therapy. Other types of thyroid cancer often re...

NEW DRUGS Cometriq for Thyroid Cancer Cabozantinib (Cometriq, Exelixis) has been approved with an orphan drug designation to treat metastatic medullary thyroid cancer (MTC). Cabozantinib blocks abnormal kinase proteins involved in the development and growth of medullary cancer cells. In a clinical study, treatment with cabozantinib increased progression-free survival and, in some patients, redu...

BACKGROUND Several studies have evaluated the association between obesity and thyroid cancer risk. However, the results remain uncertain. In this study, we conducted a meta-analysis to assess the association between obesity and thyroid cancer risk. MATERIAL/METHODS Published literature from PubMed, EMBASE, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National ...

The purpose of this study was to estimate the occurrence of familial nonmedullary thyroid cancer (FNMTC) in a large population-based study. Of the 5274 cases of thyroid cancer on record in the Norwegian Cancer Registry between 1960 and 1995, a total of 1025 patients could be identified with verified thyroid cancer, a unique personal identification number, and a link to at least one parent. For ...


 CADTH recommends that Retevmo should be reimbursed by public drug plans for the treatment of rearranged during transfection (RET)-mutant medullary thyroid cancer (MTC) patients 12 years age and older with advanced or metastatic disease if certain conditions are met.
 only covered to treat whose has progressed while taking a first-line treatment, those who cannot tolerate have contra...

Medullary thyroid cancer (MTC) is an uncommon malignancy with a high tendency to metastasize both to lymph nodes and distant localizations. In recurrent disease the most important prognostic factors are the early diagnosis, localization of the recurrent lesions and adequate patient selection for further treatment. An important role in monitoring of patients with medullary thyroid cancer plays p...

Thyroid cancer is a rare disease. Aetiological factors are increased secretion of TSH and exposure of the growing gland to ionizing radiation. Pathological classification is in two main groups: differentiated and undifferentiated. Differentiated is subdivided into papillary, follicular and medullary. Papillary and medullary carcinomas occur in young patients, grow slowly, spread by lymphatics. ...

An aim of this study is to analyze treatment results 4 patients with metastatic lesions medullary thyroid cancer (MTC) who underwent liver resection. Annually in Russian Federation 600 new cases MTC are diagnosing (0.2 per 100,000 humans). According literature, half them a distant metastasis will develop. Isolated develop up 0,5%. Resection metastases perform only small number patients. Thus, l...

This paper is part III of the series on thyroid disorders. Thyroid tumors are the most common endocrine neoplasms. Most of these tumors are benign hyperplastic or colloid nodules or benign follicular adenomas. However, 5% to 10% of the lesions that come to medical attention are carcinomas. A major clinical challenge is establishing which nodules are hyperplastic, benign, or malignant. History, ...

OBJECTIVE Thyroid cancer is the most common endocrine cancer. This review evaluates the established use of (18)F-FDG PET/CT in papillary, follicular, Hürthle cell, anaplastic, and medullary thyroid cancers. The significance of incidental diffuse and focal thyroid FDG uptake is discussed. The evolving value of non-FDG radiotracers, including (124)I, (18)F-dihydroxyphenylalanine, and (68)Ga somat...