A facile mechanochemical-based method for synthesis of copper oxide (CuO) nanoparticles is here by introduced. For this purpose, copper hydroxide powder was synthesized through a facile solution method (CuSO4 + 2 Na(OH) → Cu(OH)2 + Na2SO4) after which milling of as-prepared Cu(OH)2 precursor and NaCl resulted in the mechanochemical dehydration of Cu(OH)2 and dispersion of CuO nanoparticles into...

In this review, the recent progress in the synthesis of ureas, thioureas and guanidines by solid-state mechanochemical ball milling is highlighted. While the literature is abundant on their preparation in conventional solution environment, it was not until the advent of solvent-free manual grinding using a mortar and pestle and automated ball milling that new synthetic opportunities have opened...

We describe a simple, rapid methodology for the synthesis of water-stable iron oxide nanoparticles (IONPs) compatible with a variety of aqueous buffers, based on mechanochemical milling exchange of covalently bound surface ligands on pre-fabricated oleic acid-protected IONPs. Application of milling for IONP ligand exchange eliminates steps required for transforming hydrophobic into negatively c...

Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.

The two-step mechanochemical preparation of carbene-pyridine complexes of palladium and platinum is reported. The organometallic products, which represent a class of commercially available catalysts, are rapidly formed in excellent yield proving solvent-free synthesis to be a viable synthetic alternative even in the case of NHC-containing compounds.

For the first time, mechanochemical synthesis has been used for the preparation of crystalline and amorphous dinuclear gold(i) helicates, [Au2L2](X)2 (L = xantphos; X = CF3SO3, SCN, BF4 and PF6), that show anion- and phase-switchable luminescence properties. This solid-state approach provides strategies for developing switchable luminescent materials.

© 2012 Dushkin et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Complexes of Polysaccharides and Glycyrrhizic Acid with Drug Molecules − Mechanochem...

Mechanochemical synthesis has been used to obtain two Werner complexes and their solid solution that could not be obtained by conventional "wet" chemistry; remarkably, despite the structural and chemical similarity, the solid solution exhibits sorption properties that differ from those of the pure compounds.