Mechanical injury to connective tissue causes changes in collagen structure and material behaviour, but the role and mechanisms of molecular damage have not been established. In the case of mechanical subfailure damage, no apparent macroscale damage can be detected, yet this damage initiates and potentiates in pathological processes. Here, we utilize collagen hybridizing peptide (CHP), which bi...

The effect of mechanical agitation on the microalgae Phaeodactylum tricornutum and Porphyridium cruentum was investigated in aerated continuous cultures with and without the added shear protectant Pluronic F68. Damage to cells was quantified through a decrease in the steady state concentration of the biomass in the photobioreactor. For a given aeration rate, the steady state biomass concentrati...

Liver grafts suffer from unavoidable injury due to ischemia and manipulation before implantation. Danger signals such as high-mobility group box -1(HMGB1) and macrophage migration inhibitory factor (MIF) play a pivotal role in the immune response. We characterized the kinetics of their release into the effluent during cold/warm ischemia and additional manipulation-induced mechanical damage. Fur...

Composite materials have been used extensively in various applications, such as mechanical engineering, aerospace engineering, and aviation thanks to their interesting mechanical properties. However, a substantial drawback in the use of such composite materials is that they absorb a significant amount of moisture when exposed to severe hygrothermal conditions. This factor dramatically affects t...

A coupled elastoplastic-damage constitutive model taking into account chemo-induced elastoplastic-damage effects for the modeling of coupled chemothermo-hygro-mechanical behavior of concretes at high temperature is proposed in this article. A three-step operator split algorithm for the integration of the rate coupled constitutive equations is developed. Consistent tangent modulus matrices for c...

In this paper, the reasons of damage water pumps parts of the air compressor cooling system were studied. To reach this goal, the works like preparing metallographic samples, evaluation of structure, investigation of mechanical properties, the alloy parts detection and chemical analysis of deposit and corrosion products collected from the parts were performed. According to studies and results o...

In this paper, the reasons of damage water pumps parts of the air compressor cooling system were studied. To reach this goal, the works like preparing metallographic samples, evaluation of structure, investigation of mechanical properties, the alloy parts detection and chemical analysis of deposit and corrosion products collected from the parts were performed. According to studies and results o...

We consider the quasistatic Signorini’s contact problem with damage for elastic-viscoplastic bodies. The mechanical damage of the material, caused by excessive stress or strain, is described by a damage function whose evolution is modeled by an inclusion of parabolic type. We provide a variational formulation for the mechanical problem and sketch a proof of the existence of a uniqueweak solutio...

The purpose of the present study was to investigate the context of new aspects of cellular adaptation in physical activity with a focus on delayed pain approach, the nature and types of pain, several preventive and non-pharmacological approaches to delayed onset muscle soreness (DOMS) and to achieve a desirable conclusion and provide more relevant information from previous research. In this stu...