BACKGROUND Chronic kidney disease (CKD) represents an increasing health burden. We present the population-based prevalence of CKD and compare the CKD Epidemiology collaboration (CKD-EPI) and modification of diet in renal disease (MDRD) equations to estimate the glomerular filtration rate, using the revised CKD classification with three albuminuria classes. We also explore factors associated wit...

A study of glomerular filtration rate estimation by cockcroft-gault, mdrd and ckd-epi formula in comparison with dtpa renal scan – a comparative study among live related kidney donors in south india. a b c Original Article BACKGROUND: Renal function assessment is the most important part of donor evaluation. The Glomerular Filtration Rate (GFR) is considered to be optimal test for overall assess...

The aim of this paper was to study the estimated glomerular filtration rate (eGFR), its changes with age, and its association with systolic blood pressure (SBP) and diastolic BP (DBP), indicators of obesity, dyslipemia, insulin resistance and inflammation on a random population sample. BP, weight, size and waist circumference (WC) were recorded at home. Fasting morning blood samples were analys...

INTRODUCTION Serum cystatin C is more sensitive for glomerular filtration rate (GFR) measurement, but it is not available for clinical use in all laboratories. Regarding the importance of accurate estimation of GFR in kidney transplant recipients, we compared cystatin C-based equations with creatinine-based formulas to estimate GFR as precisely and simply as possible in kidney transplant recipi...

BACKGROUND Accurate measurement of renal function is important: however, radiolabelled gold standard measurement of GFR is highly expensive and can only be used on a very limited scale. We aim to compare the performance of Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equations in the multi-ethnic population attending University Mal...

BACKGROUND Fatty acid-binding protein 4 (FABP4) has been linked to metabolic syndrome development, diabetes, and arteriosclerosis, but the role of FABP4 in target organ damage has not been assessed. We evaluated whether plasma FABP4 is associated with renal dysfunction in type 2 diabetic patients. METHODS In 263 individuals (161 type 2 diabetic patients and 102 healthy nondiabetic controls), ...

BACKGROUND Cockcroft-Gault (CG) and Modification of Diet in Renal Disease (MDRD) formulae are recommended for glomerular filtration rate (GFR) estimation, but neither has been validated or directly compared longitudinally in HIV-infected patients or in Africa. METHODS We investigated differences between formulae in baseline GFR, GFR changes and incidence of impaired GFR after initiation of an...

BACKGROUND Three equations have been often used to estimate glomerular filtration rate (GFR), namely, Modification of Diet in Renal Disease (MDRD), MDRD for Chinese (MDRDc), and Cockcroft-Gault (CG), for the purpose of screening individuals with chronic kidney disease (CKD). However, neither of these equations has been tested in a large Asian population. The aim of this study was to determine w...

BACKGROUND Accurate evaluation of the glomerular filtration rate (GFR) in patients awaiting liver transplantation is important because they have a greater risk of impaired renal function. A major percentage of these patients have alcoholic cirrhosis, and the accuracy of bedside used GFR estimates have not been specifically evaluated in this group. The aim of this study was to evaluate the valid...

AIMS This study evaluates the prognostic utility of renal dysfunction estimated by the recently validated modification of diet in renal disease (MDRD) equations and compares it with the currently most promising predictor of prognosis in patients with advanced heart failure. METHODS AND RESULTS We prospectively studied 182 consecutive patients with advanced chronic heart failure (CHF) referred...