A lthough the recent identification of the mitochondrial Ca 2+ uniporter (MCU) has resolved a long-standing mystery as to how Ca 2+ freely enters the mitochondria, it has also evoked additional questions such as its mode of regulation and the identity of other associated factors. In an article recently published in Nature, Joiner et al 1 provide data demonstrating that in the heart, matrix-loca...

This paper proposes a dynamic synchronous capture (DSC) algorithm to calculate the flow rate for an electromagnetic flowmeter. The characteristics of the DSC algorithm can accurately calculate the flow rate signal and efficiently convert an analog signal to upgrade the execution performance of a microcontroller unit (MCU). Furthermore, it can reduce interference from abnormal noise. It is extre...

Individual synapses vary significantly in their neurotransmitter release properties, which underlie complex information processing in neural circuits. Presynaptic Ca2+ homeostasis plays a critical role in specifying neurotransmitter release properties, but the mechanisms regulating synapse-specific Ca2+ homeostasis in the mammalian brain are still poorly understood. Using electrophysiology and ...

This article proposes a measurement system controlled by microcontroller unit (MCU) for the electronic reading of mechanical gas meter. The relies on dual magnetic sensing: 1) low-cost low-power primary sensing based reed switches connected to digital inputs MCU, and 2) secondary Hall-effect sensors analogue MCU. In addition, both strategies have an active passive element achieve output insensi...

Background—Impairment of intracellular Ca homeostasis and mitochondrial function has been implicated in the development of cardiomyopathy. Mitochondrial Ca uptake is thought to be mediated by the Ca uniporter (MCU) and a thus far speculative non-MCU pathway. However, the identity and properties of these pathways are a matter of intense debate, and possible functional alterations in diseased sta...

BACKGROUND Delirium is a frequently occurring syndrome in patients admitted to the intensive care unit (ICU) or medium care unit (MCU), yet the pathophysiology remains poorly understood. An excess of central serotonin can lead to an altered mental status, associated with autonomic hyperactivity, and neuromuscular excitation. Drugs with serotonergic properties are frequently and for prolonged pe...

In this paper, an in-situ microfluidic control unit (MCU) was designed and applied in a hydrothermal synthesis process, which provides an easy way to localize liquid-phase reaction and realize selective synthesis and direct growth of nanostructures as well as their morphology, all in a low-temperature and atmospheric environment. The morphology was controlled through controlling the amount of a...

Four types of commercial mosquito control traps, the Mosquito Magnet Pro (MMP), the Sentinel 360 (S360), the BG-Sentinel (BGS), and the Mega-Catch Ultra (MCU), were compared with a standardCenters forDiseaseControl andPrevention (CDC) light trap for efÞcacy in collecting phlebotomine sand ßies (Diptera: Psychodidae) in a small farming village in the Nile River Valley 10 km north of Aswan, Egypt...

Mitochondria receive calcium (Ca(2+)) signals from endoplasmic reticulum (ER) and decode them into pro-apoptotic inputs, which lead to cell death. Therefore, mitochondrial Ca(2+) overload is considered a fundamental trigger of the apoptotic process, and several oncogenes and tumor suppressors modify the activity of protein involved in Ca(2+) homeostasis to control apoptosis. The identification ...

Nowadays SCADA (Supervisory Control and Data Acquisition) systems became widely used technology. This fact is directly related to the ubiquity of smart systems using a wide range of technologies in control and supervision applications. MCU technology are a very promising technology in this field especially, with the emergence of safety critical MCU, cost/power reduction and wireless connectivit...