Objectives: In this article, a new procedure for increasing the light penetration depth in a tissue is studied and simulated. It has been reported that the most important problem in biomedical optical imaging relates to the light penetration depth, and so this makes a dramatic restriction on its applications. In the optical imaging method, the detection of the backscattered pho...

In this paper we report the design, testing and use of a scannerless probe specifically for minimally invasive imaging of deep tissue in vivo with an epi-fluorescence modality. The probe images a 500 μm diameter field of view through a 710 μm outer diameter probe with a maximum tissue penetration depth of 15 mm specifically configured for eGFP imaging. Example results are given from imaging the...

Recent measurements of the superconducting penetration depth in Ba(Fe1 xCox)2As2 appeared to disagree on the magnitude and curvature of Dkab(T), even near optimal doping. These measurements were carried out on different samples grown by different groups. To understand the discrepancy, we use scanning SQUID susceptometry and a tunnel diode resonator to measure the penetration depth in a single s...

Ion beam diagnostics are routinely used for quantitative analysis of the surface composition of mixture materials up to a depth of a few m. Unfortunately , advantageous properties of the diagnostics, like high depth resolution in combination with a large penetration depth, no destruction of the surface, high sensitivity for large as well as for small atomic numbers, and high sensitivity are mut...

Temporal focusing is a technique for performing axially resolved widefield multiphoton microscopy with a large field of view. Despite significant advantages over conventional point-scanning multiphoton microscopy in terms of imaging speed, the need to collect the whole image simultaneously means that it is expected to achieve a lower penetration depth in common biological samples compared to po...