Background and Aims: Infectious bursal disease (IBD) is an acute contagious viral disease of birds worldwide. The causative virus induces a persistent immune suppression following destroy B lymphocytes precursors in bursal lymphoid follicles. Vaccination is the main strategy for prevention of the disease in commercial poultry industry. Materials and Methods: To produce a live vaccine against th...

equine influenza is an acute, infectious and highly contagious respiratory disease with worldwide distribution and high morbidity and low mortality. the disease caused by h7n7 and h3n8 subtypes of genus (type) a of influenza virus. the most significant clinical signs of this disease are fever, coughing and nasal discharge. in this study, the presence of antibody against two subtypes of equine i...

background and aims: newcastle disease virus (ndv) is an avian paramyxovirus (a-pmv 1) and one of the major pathogens in poultries. vaccination is intended to control the disease, nevertheless this virus is a growing threat to the poultry industry. so, early detection of the virus can prevent the spread of illness and avoid huge economic losses. towards this goal, in this research, we developed...

background: crimean-congo hemorrhagic fever (cchf) is a feverous and hemorrhagic disease endemic in some parts of iran and caused by an arbovirus related to bunyaviridae family and nairovirusgenus. the main virus reser­voir in the nature is ticks, however small vertebrates and a wide range of domestic and wild animals are regarded as reservoir hosts. this study was conducted to determine the in...

Background and Aims: Respiratory syncytial virus (RSV) infection is common in infants and young children. In infants younger than one year old it may cause bronchiolitis and pneumonia which requires hospitalization. Accurate and rapid diagnosis of the disease will help proper treatment of the disease and prevents further complications. Methods: Specimen taken from respiratory tract of sick chil...

there are several important mosquito borne infectious disease in the tropical countries. chikungunya virus infection is an important arbovirus in this group. we hereby used a standard medicogeographical analysis to assess the correlation between prevalence of chikungunya virus infection and rainfall in the endemic area of thailand, the southern region. in this work, the correlation was poor but...

results in 12 patients (37%), human papilloma virus was detected by pcr method. in addition, there was no difference in distribution of patients with respect to affliction with human papilloma virus between high-risk and low-risk groups. there was no relationship between clinical manifestation and type of papilloma virus. materials and methods this cross-sectional study was conducted on 32 pati...

we have analyzed paraffin sections from 55 patients with histologically confirmed hodgkin’s disease (hd) for the presence of epstein-barr virus (ebv) markers using in situ hybridization to detect the ebv-encoded rnas (ebers) and immunohistochemistry to identify latent membrane protein-1 (lmp1) expression. tissue specimens from 55 cases of hodgkin’s disease included 22-mixed cellularity (mc), 27...

hemophagocytic lymphohistiocytosis (hlh) is one of the complications of epstein-barr virus (ebv) infection. although the patients who have developed hlh following ebv have normal immune system, there are a few patients with ebv-induced immune deficiency who develop hlh as well. here, we describe the case of a 10-year-old girl with neurological complications caused by ebv-induced hlh. the patien...

foot and mouth disease (fmd) is highly contagious disease among cloven-hoofed animals. fmd virus has structural and non-structural proteins. vp1 is the most immunogenic structural peptides of fmd virus, applied for major vaccine studies. objective: construction of pet28-vp1 cassette for fmd virus type o/irn/2010 and expression vp1 peptide as the most immunogenic antigen was the aim of this stud...