Immunoglobulin concentrations and lymphocyte counts were determined in bronchoalveolar fluid obtained from nine symptomless, healthy, non-smoking granite workers (mean age 45.6, range 22-56 years) and nine normal, non-smoking, non industrial controls (mean age 22.8, range 21-32 years). The proteins were measured in unconcentrated lavage fluid by means of a solid phase, enzyme linked immunosorbe...

A major obstacle to the development of effective treatment of Alzheimer's disease (AD) is successfully delivery of drugs to the brain. We have previously identified a series of benzothiazole phosphonate compounds that block the interaction of amyloid-β peptide with amyloid-β binding alcohol dehydrogenase (ABAD). A selective and sensitive method for the presence of three new benzothiazole ABAD i...

Current strategies for the treatment of Alzheimer's disease (AD) involve tackling the formation or clearance of the amyloid-beta peptide (Aβ) and/or hyper-phosphorylated tau, or the support and stabilization of the remaining neuronal networks. However, as we gain a clearer idea of the large number of molecular mechanisms at work in this disease, it is becoming clearer that the treatment of AD s...

CDF and Granite: A Comparison Master's Project Report Lorna Ellis May 2004 Abstract Because large scientific datasets are often stored in files, efficient data analysis depends on efficient I/O and data manipulation tools. The Granite Scientific Database System is a system that incorporates database methodology and spatial semantics to support retrieval and visualization of scientific data. CDF...

In this study, production possibility of glass and glass-ceramic produced from granite was investigated. The composition of granite based glass bath mixture was 50 wt% granite, 25 wt% dolomite and 25 wt% sodium carbonate. Composition that was grounded and mixed in a ball mill for 2 h was melted at 1500 ◦C for 1 h. Glass samples were heat treated for crystallization to produce glass-ceramic mate...

Pecoits et al. (Reports, 29 June 2012, p. 1693) describe bilaterian trace fossils and assign them an Ediacaran age based on the age of a granite interpreted as intrusive. We argue that the granite is not intrusive but in fact represents the basement of the sedimentary succession. Moreover, we show that identical trace fossils occur in nearby Carboniferous-Permian glacigenic rocks.

In the present study, plate-impact experiments are employed to better understand the stress threshold for inelasticity in Westerly granite. The experiments are designed to obtain the Hugoniot Elastic Limit (HEL) as well as spall strength following shock-induced compression in the Westerly granite samples. The HEL for Westerly granite is estimated to be in the range 3.2 to 3.5 GPa, while the spa...

The Xihuashan granitic complex (southern China) is mainly composed of coarse-grained porphyritic biotite granite (G–a), medium-grained porphyritic biotite granite (G–b), and mediumto fine-grained porphyritic biotite granite (G–c). The G–a granite is characterized by monazite-(Ce) and xenotime-(Y), in addition to commonly observed zircon and uranoan thorite. In the G–b and G–c intrusive units, m...

45 granite crushers and 45 age and smoking matched referents underwent pulmonary function tests in 1976 and 1988. On average, the granite crushers at follow up had worked for 22 years, were 52 (range 36-78) years old, and had inhaled a cumulated amount of 7 mg of silica in the respirable dust fraction. Between 1976 and 1988 the average concentration of respirable quartz in air was 0.16 mg/m3 (t...

In a Perspective accompanying Abad-Franch and colleagues, Lorenz von Seidlein, Alexander Kekulé, and Daniel Strickman discuss the importance of developing effective strategies to minimize mosquito-borne transmission of human diseases.