We observe traveling waves emitted from Turing spots in the chlorine dioxide-iodine-malonic acid reaction. The newborn waves are continuous, but they break into segments as they propagate, and the propagation of these segments ultimately gives rise to spatiotemporal chaos. We model the wave-breaking process and the motion of the chaotic segments. We find stable segmented spirals as well. We att...

inborn errors of organic acid metabolism are relatively recently recognized diseases with a wide spectrum of clinical signs and symptoms: ranging from asymptomatic, normal appearing children to death during first few days of life.in my presentation i will try to explain some of the most common clinical presentation of these disorder with stress on neurologic findings. organic acidemia usually h...

In earlier communications we described the re­ sults of an investigation of the main products of the oscillating oxidation of malonic acid by bromate 1. The products were identified as monobromomalonic acid, dibromoacetic acid and C02 . Also, the relative quantities of the two organic products were deter­ mined. Current hypothesis on the mechanism of the reac­ tion pathway under oscillating con...

In this work we present results about the deuterium isotope effect on the global kinetics of a Belousov-Zhabotinsky reaction in batch conditions. A nonlinear dependence of the Induction Period upon the percentage of deuterated reactants was found. The isotopic effect on the bromination reaction of malonic acid was evaluated.

INTRODUCTION In vivo pH imaging has been a field of interest for molecular imaging for many years. This is especially important for determining tumor acidity, an important driving force of tumor invasion and metastasis formation, but also in the process of apoptosis. METHODS 2-(4-[(123)I]iodophenethyl)-2-methylmalonic acid (IPMM), 2-(4-[(123)I]iodophenethyl)-malonic acid (IPM), 2-(4-[(123)I]i...

This study was conducted to improve four characteristics as objectives:（1） high current efficiency, （2） surface brightness, and （3） hardness of chromium-carbon （Cr-C） alloy layers during electrochemical deposition from Cr（III） ions, （4） reproducibility the Cr-C layer formation repeated plating with a electroplating bath. A malonic-acid-containing sulfuric acid bath （sulfuric II） prepared by add...

The synthesis of new α,β-unsaturated furanuronic acid derivatives of α-gluco-, β-gluco- and β-manno-chloraloses via a convenient one pot procedure using the Knoevenagel-Doebner reaction approach are described. The dialdofuranose derivatives were reacted with malonic acid under Knoevenagel-Doebner reaction conditions and (E)-α,β-unsaturated furanuronic acid derivatives were obtained.

HIV-1 integrase (IN) is an attractive and validated target for the development of novel therapeutics against AIDS. In the search for new IN inhibitors, we designed and synthesized three series of bis-amide and hydrazide-containing derivatives of malonic acid. We performed a docking study to investigate the potential interactions of the title compounds with essential amino acids on the IN active...