نتایج جستجو برای: malignant peripheral nerve sheath tumor

تعداد نتایج: 873020  

Journal: :Journal of the National Comprehensive Cancer Network 2013

2018
Christopher A. D’Angelis David M. Crossland

Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma arising from neuroectoderm-derived cells comprising the outer coverings of peripheral nerves. Given the diverse cell types comprising the peripheral nerve sheath, both benign and malignant nerve sheath tumors display a wide range of histologic appearances. MPNST can arise either in association with proximal nerve trun...

Journal: :Anais da Academia Brasileira de Ciencias 2013
Karin S Cunha Anabela C Caruso Paulo A Faria Licínio E da Silva Eliene C da Fonseca Mauro Geller Rodrigo S de Moura-Neto Vânia S Lopes

AIMS To study the expression of Bcl-2, Bcl-x, as well the presence of cleaved caspase-3 in neurofibromas and malignant peripheral nerve sheath tumors. The expression of Bcl-2 and Bcl-x and the presence of cleaved caspase 3 were compared to clinicopathological features of malignant peripheral nerve sheath tumors and their impact on survival rates were also investigated. MATERIALS AND METHODS T...

Journal: :Neurosurgery 2011
Kristophe J Karami Prashant S Kelkar Michael P Verdon Inga S Grills Dennis I Bojrab Daniel R Pieper

BACKGROUND AND IMPORTANCE Malignant peripheral nerve sheath tumors are the most common malignant mesenchymal tumors of soft tissues, but they are very rare when found to arise from a cranial nerve and when not in association with neurofibromatosis. These tumors are highly malignant and carry a poor prognosis with survival usually less than 6 months. CLINICAL PRESENTATION The authors report th...

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