background : β-thalassemia trait is one of the most common genetic disorders in mediterranean countries. previous studies have shown that β- thalassemia trait has a protective effect against malaria, coronary artery disease, hypertension and alzheimer disease. we hypothesize that due to the shorter life span of red blood cells and increased hematopoiesis, these patients are at increased risk of...

abstract background data on childhood and adolescent malignant tumors incidence are skimp in developing countries. in this study, we analyzed the incidence and trend of childhood and adolescent cancers in yazd city, center of iran between jan 2004 and dec 2013. materials and methods the various types of malignant tumors were grouped pursuant to the international classification for cancer in chi...

BACKGROUND In the combined antiretroviral therapy (cART) era, non-acquired immunodeficiency syndrome (AIDS)-defining malignancies account for more morbidity and mortality in human immunodeficiency virus-infected patients than AIDS-defining malignancies. However, conflicting data have been reported on the relationship between immunodeficiency and the development of some non-AIDS-defining maligna...

Introduction: Radiotherapy is a common treatment modality for patients with head and neck malignancies. As the nose lies within the field of radiotherapy of the head and neck, the olfactory fibers and olfactory receptors may be affected by radiation. The aim of this study was to evaluate changes in olfactory threshold in patients with head and neck malignancies who have received radiation to th...

Introduction: Sinonasal malignancies are uncommon neoplasms with several histological subtypes. These malignancies have a poor prognosis and, because of the nonspecific nature of the symptoms, most patients are diagnosed late when the disease is already at an advanced stage. Therefore, most sinonasal malignancies tend to be treated with surgery and postoperative radiotherapy. Understanding the ...

OBJECTIVE We noticed that a significant proportion of our patients with head and neck mucoepidermoid carcinoma (HNMEC) had second primary malignancies. To our knowledge, such an association has never been described. The aim of our study is to elucidate the association between second primary malignancies and HNMEC. STUDY DESIGN Case series with chart review. SETTING Tertiary referral center....

BACKGROUND Cancer is now the leading cause of death in persons with HIV. In this study, we gathered current epidemiological data on Aids-defining (AD) and non-Aids-defining (NAD) malignancies among HIV-positive patients in Germany. METHODS From 2000 to 2007, all 35 specialized HIV outpatient clinics and 189 HIV ambulatory care centers in Germany were contacted and asked to fill out a structur...

Background: The increase in the incidence of malignancies globally, and usage frequency types new anti-cancer drugs, have made onconephrology more important our clinical practice. Paraneoplastic glomerulonephritis constitutes an part this approach as well. Purpose: association AML-nephrotic syndrome is relatively less defined literature compared to other hematological malignancies. Case present...