background:  depression is the world’s fourth most prevalent health problem which is ‎associated with substantial mortality, direct medical cost, diminished life quality, and ‎significant physical and psychosocial impairment. this study aimed to investigate the ‎effect of psycho-educational intervention on the life quality of major depressive patients.‎ materials and methods:  sixty patients wh...

depressive disorders are more common among persons with chronic diseases such as inflammatory bowel disease and anti-inflammatory effect of some antidepressants such as amitriptyline has been reported. acetic acid colitis was induced in both reserpinised (depressed) and non-reserpinised (normal) rats. reserpinised groups received reserpine (6 mg/kg, i.p.) one hour prior to colitis induction. th...

background: major depression is a common disorder with great social and individual burdens. transcranial sonography (tcs) is a useful and noninvasive measure for assessment of normal and impaired brain parenchyma. the brainstem raphe nuclei are in close association with dorsocaudal limbic system and plays an important role in depression. in this study we compared the echogenicity of the raphe n...

Prevalence rates of depressive disorders in Parkinson's disease (PD) vary widely across studies, ranging from 2.7% to more than 90%. The aim of this systematic review was to calculate average prevalences of depressive disorders taking into account the different settings and different diagnostic approaches of studies. Using Medline on Pubmed, a systematic literature search was carried out for st...

introduction: depression and anxiety, in particular panic disorder are considered common psychological problems associated with major functional disorders. on the other hand, some medical disorders such as thyroid disease may have the same manifestation or accelerate the process. this following is a closer examination of the issue trough the study of a group of patients referred to a psychiatri...

SUMMARY The new diagnostic category in the Depressive Disorders chapter of DSM-5 entitled 'Major Depressive Disorder With Mixed Features' is applied to individuals who meet criteria for Major Depressive Disorder and have concurrent subsyndromal hypomanic or manic symptoms. But the operational definition of this new specifier is much closer to that of hypomania and mania than to the definition o...

CONTEXT Controversy surrounds the diagnostic categorization of generalized anxiety disorder (GAD). OBJECTIVES To examine the incidence, comorbidity, and risk patterns for anxiety and depressive disorders and to test whether developmental features of GAD more strongly support a view of this condition as a depressive as opposed to an anxiety disorder. DESIGN Face-to-face, 10-year prospective ...

introduction & objective: patients with major depressive are difficult to treat, and the relative efficacy of medications and cognitive therapy in the treatment of depression is still a matter of deabath. the purpose of this study was to compare the efficacies of antidepressant medication, cognitive therapy and combination of cognitive therapy and antidepressant medication. materials & methods:...

BACKGROUND In January 2002 the New York City Chapter of the National Multiple Sclerosis Society convened a panel of experts to review the issue of depressive affective disorders associated with multiple sclerosis (MS). This Consensus Conference was supported by a grant from the Goldman family of New York City. RESULTS The panel reviewed summaries of current epidemiologic, neurobiologic, and t...