Leptin, a major adipocytokine produced by adipocytes, is emerging as a key molecule linking obesity with breast cancer therefore, it is important to find effective strategies to antagonize oncogenic effects of leptin to disrupt obesity-cancer axis. Here, we examine the potential of honokiol (HNK), a bioactive polyphenol from Magnolia grandiflora, as a leptin-antagonist and systematically elucid...

The Tennessee (Vermivora peregrina), Cape May (Dendroica tigrina), Bay-breasted (D. castanea), and Canada (Wilsonia canadensis) warblers and the Ovenbird (Seiurus aurocapillus) appear to show positive numerical responses to outbreaks of the spruce budworm (Choristoneura fumiferana); the Magnolia (D. magnolia), Black-throated Green (D. virens), and Blackburnian (D. fusca) warblers may occur in l...

Magnolia sprengeri Pamp. is an ornamentally and ecologically important tree that blooms at cold temperatures in early spring. In this study, thermogenesis and variation in the chemical compounds of floral odours and insect visitation in relation to flowering cycles were studied to increase our understanding of the role of floral thermogenesis in the pollination biology of M. sprengeri. There we...

The antimicrobial killing activity toward methicillin-resistant Staphylococcus aureus (MRSA) has been a serious emerging global issue. In a continuing search for compounds with antibacterial activity against several microorganisms including S. aureus and MRSA, an n-hexane extract of Magnolia officinalis was found to contain magnolol. This compound exhibited potent activity against S. aureus, st...

David Hume and Adam Smith are considered the founding fathers of anti-mercantilism, economics, and the Scottish Enlightenment. However, scholars have long recognized a similarity between Hume’s contributions and those of Richard Cantillon. Evidence is presented here that suggests that Hume would have known of Cantillon and would have been interested in reading the manuscript, and that he met pe...

1Department of Preventive Veterinary Medicine, Faculty of Veterinary and Animal Science, Universidad de Chile, Santiago, Chile; 2PhD Program in Agriculture, Forestry and Veterinary Science, Universidad de Chile, Santiago, Chile; 3Emerging and Reemerging Zoonoses Research Network, Santiago, Chile; 4Universidad Nacional Andres Bello, Santiago, Chile; 5Center of Veterinary Medicine, Universidad Na...