Stereoselectivity in drug metabolism can not only influence the pharmacological activities, tolerability, safety, and bioavailability of drugs directly, but also cause different kinds of drug-drug interactions. Thus, assessing stereoselectivity in drug metabolism is of great significance for pharmaceutical research and development (R&D) and rational use in clinic. Although there are various met...

Widespread arsenic contamination of mining wastewater of Zarshouran (West Azerbaijan province) has led to a massive epidemic of arsenic poisoning in the whole of surrounding areas. It is estimated that approximately all agriculture fields are being irrigated with the water that its arsenic concentrations elevated above the World Health Organization’s standard of 10 parts per billion. A novel ad...

background: hydatidosis it is a zoonotic disease which is caused by the larval stages of different species of the tapeworms (cestoda) of genus echinococcus. currently, the surgery is most definitive method of treatment for hydatid cyst, but always there is the risk of leakage or rupture during the surgery, therefore it is considered unreliable method. methods: protoscoleces of hydatid cysts wer...

the response rate to the treatment of obsessive compulsive disorder (ocd) is 21.6% to 61.3%, which shows a relative resistance to current treatments and a need for novel therapeutic approaches. here we report a case of resistant ocd with fast and dramatic response to a relatively new method of repeated transcranial magnetic stimulation. in this method a pulse magnetic field  emits from a coil o...

results in the control group, barthel and fugl-meyer indices showed significant improvement (p = 0.01, p = 0.00), while in the experimental group, significant improvement in barthel and fugl-meyer indices and dynamometers has been observed (p = 0.01, p = 0.00, p = 0.007). conclusions rtms can improve hand muscle force and functions of patients with chronic hemiplegia, while conventional treatme...