magnesium sulfate is widely used in obstetrics and is drug of choice in two important complications of pregnancy, preeclampsia and preterm labor. the antagonistic effects of magnesium sulfate on calcium ion and on platelet aggregation may lead to changes in bleeding time. this study was conducted to evaluate the effect of magnesium sulfate on bleeding time in women with threatened preterm labor...

Myofibrils which lengthen by several per cent in the presence of ATP and magnesium ions were prepared by teasing indirect flight muscle of Drosophila in solutions containing ethylenediaminetetraacetate. A study was made of the hydrogen ion, magnesium ion, ATP, and potassium chloride concentrations with which this effect could be observed. The lack of elongation with pyrophosphate and several nu...

Citation Canepa, Pieremanuele, Saivenkataraman Jayaraman, Lei Cheng, Nav Nidhi Rajput, William D. Richards, Gopalakrishnan Sai Gautam, Larry A. Curtiss, Kristin A. Persson, and Gerbrand Ceder. “Elucidating the Structure of the Magnesium Aluminum Chloride Complex Electrolyte for Magnesium-Ion Batteries.” Energy Environ. Sci. 8, no. 12 (2015): 3718–3730. © 2015 Royal Society of Chemistry As Publi...

Placing metal ions into the center of a porphyrin ring is a significant cellular challenge. Lundqvist et al. (2010) provide snapshots of the AAA+ motor unit of magnesium chelatase, an enzyme that inserts a magnesium ion into the porphyrin ring accompanied by ATP expenditure, in different states of binding to adenosyl nucleotides.

In laboratory sandpack tests for heavy oil recovery by alkaline flooding, it was found that wettability alteration of the sand had a significant impact on oil recovery. In this work, a heavy oil of 14 API was used to examine the effect of organic acids in the oil and water chemistry on wettability alteration. From interfacial tension measurements and sand surface composition analysis, it was c...

It is suggested that under physiological conditions (> 1 mM Mg(2+)) MgATP binds to myosin to form a chelate involving the two reactive sulfhydryl sites (SH(1) and SH(2)). The stability of the chelate structure results in marked inhibition of the myosin ATPase in the presence of millimolar magnesium ion. The inhibitory effect of magnesium ion can be eliminated chemically by blocking either the S...

The substrate shape specificity of the Escherichia coli ribonuclease P (RNase P) ribozyme depends on the concentration of magnesium ion. At 10 mM or more, it can cleave a hairpin substrate as well as a cloverleaf pre-transfer RNA (tRNA). The results showed, however, that the holo enzyme cleaved the hairpin substrate at low concentrations of magnesium ion. Considering that the homologous E. coli...

The hammerhead ribozyme undergoes a well-defined two-stage conformational folding process, induced by the binding of magnesium ions. In this study, we have used isothermal titration calorimetry to analyze the thermodynamics of magnesium binding and magnesium ion-induced folding of the ribozyme. Binding to the natural sequence ribozyme is strongly exothermic and can be analyzed in terms of seque...

Magnesium ions play important roles in the structure and function of nucleic acids. Whereas the tertiary folding of RNA often requires magnesium ions binding to tight places where phosphates are clustered, the molecular basis of the interactions of magnesium ions with RNA helical regions is less well understood. We have refined the crystal structures of four decamer oligonucleotides, d(ACCGGCCG...

BACKGROUND Underground water is an important natural resource serving as a reliable source of drinking water for many people worldwide, especially in developing countries. Underground water quality needs to be given a primary research and quality control attention due to possible contamination. This study was therefore designed to determine the physico-chemical and bacteriological quality of bo...