OBJECTIVE The aim of this study was to examine whether and to what extent magnesium intake is related to systemic inflammation and the metabolic syndrome. RESEARCH DESIGN AND METHODS We performed a cross-sectional analysis on data from 11,686 women > or =45 years of age participating in the Women's Health Study who were initially free of cardiovascular disease and cancer and had no use of pos...

OBJECTIVES The aim of this study was to examine whether magnesium intake is associated with coronary artery calcification (CAC) and abdominal aortic calcification (AAC). BACKGROUND Animal and cell studies suggest that magnesium may prevent calcification within atherosclerotic plaques underlying cardiovascular disease. Little is known about the association of magnesium intake and atherosclerot...

The purpose of this study was to investigate magnesium nutritional status and its association with asthma in elementary school children (1277 boys and 1109 girls) participating in the Nutrition and Health Survey in Taiwan (NAHSIT children 2001-2002). Dietary magnesium intake was based on 24-hour dietary recalls. Serum magnesium was measured. Average magnesium intake was 247 mg and 228 mg for th...

In comparison with calcium, magnesium is an "orphan nutrient" that has been studied considerably less heavily. Low magnesium intakes and blood levels have been associated with type 2 diabetes, metabolic syndrome, elevated C-reactive protein, hypertension, atherosclerotic vascular disease, sudden cardiac death, osteoporosis, migraine headache, asthma, and colon cancer. Almost half (48%) of the U...

OBJECTIVE Although magnesium may favorably affect metabolic outcomes, few studies have investigated the role of magnesium intake in systemic inflammation and endothelial dysfunction in humans. RESEARCH DESIGN AND METHODS Among 3,713 postmenopausal women aged 50-79 years in the Women's Health Initiative Observational Study and free of cardiovascular disease, cancer, and diabetes at baseline, w...

BACKGROUND It has been reported that adequate calcium intake decreases body fat and appropriate intakes of magnesium suppress the development of the metabolic syndrome. Furthermore, lactulose increases the absorption of calcium and magnesium. An optimal combination of calcium, magnesium and lactulose may therefore reduce body fat mass. METHODS An open-label randomized controlled trial was con...

INTRODUCTION Magnesium is an essential element that has numerous biological functions in the cardiovascular system. Hence, three hundred patients with known cardiovascular disease above the age of 25 years were studied to evaluate association between dietary and serum magnesium with cardiovascular risk factors. MATERIALS AND METHODS Patients were divided into three groups according to serum m...

Magnesium is an essential ion that has an important role in regulating cell cycles and maintaining genomic stability (1). Administration of supplemental magnesium in animals with experimentally induced colon cancer resulted in fewer colon tumors and smaller cryptal cells of the colon (2), suggesting an inhibitory role of magnesium in colon cancer cell proliferation. The mechanism by which magne...

BACKGROUND Previously, we showed that black girls retained more calcium than white girls did and that salt loading negatively affected calcium retention. Racial differences likely exist in other bone minerals also, such as magnesium, in response to salt loading during growth. OBJECTIVE We studied racial differences in magnesium metabolism in response to dietary sodium and calcium during rapid...

Magnesium is an essential ion that has an important role in regulating cell cycles and maintaining genomic stability (1). Administration of supplemental magnesium in animals with experimentally induced colon cancer resulted in fewer colon tumors and smaller cryptal cells of the colon (2), suggesting an inhibitory role of magnesium in colon cancer cell proliferation. The mechanism by which magne...