Background Antiplatelet therapy (APT) is known to substantially reduce mortality and rate of ischaemic complications after coronary artery bypass grafting (CABG). Rate of perioperative APT resistance varies widely and could be influenced by cardiopulmonary bypass (CPB). The purpose of the study was perioperative assessment of platelet function with respect to administered APT and CPB, and deter...

The reliability of the radio frequency (RF) windows on the Low Energy Demonstration Accelerator (LEDA) is critical to the success of the Accelerator Production of Tritium Program (APT). On the APT accelerator there will be over 1000 windows, each passing on the order of 250 kW of CW RF power. This power level is well above power levels historically used in RF windows. Based on the high-power RF...

Metal-based drugs are largely undeveloped in pharmacology. One limiting factor is the systemic toxicity of metal-based compounds. A solid-phase, sequestratable delivery agent for local delivery of metals could reduce systemic toxicity, facilitating new drug development in this nascent area. Amorphous peroxotitanates (APT) are ion-exchange materials with high affinity for several heavy metal ion...

Abstract The Fe-Cr metastable miscibility gap has been studied by high-precision thermal treatments, Vickers micro-hardness (HV) measurements, and atom probe tomography (APT). Thermodynamic modeling further supplements the experimental work. results obtained show that recent thermodynamic descriptions of found in literature generally overestimates consolute temperature. We can source ambiguity ...

We describe the development of Analytic Perturbation Theory (APT) in QCD, called Fractional APT (FAPT), which has been suggested to apply the renormalization group evolution and QCD factorization technique in the framework of APT. 1 Basics of APT in QCD In the standard QCD Perturbation Theory (PT) we have: ✔ the Renormalization Group (RG) equation das(L)/dL = −as − c1 as − . . . for the effecti...

The transcription factor FOXM1 binds to its consensus sequence at promoters through its DNA binding domain (DBD) and activates proliferation-associated genes. The aberrant overexpression of FOXM1 correlates with tumorigenesis and progression of many cancers. Inhibiting FOXM1 transcriptional activities is proposed as a potential therapeutic strategy for cancer treatment. In this study, we obtain...

BACKGROUND Antiplatelet therapy (APT) was prevalently being used in the prevention of vascular disease, but the influence of prior APT on the prognosis of patients with intracerebral hemorrhage (ICH) remains controversial. This meta-analysis was to explore the effects of prior APT on the prognosis of patients with primary ICH. METHODS PubMed and Embase were searched to identify the eligible s...

Purpose. This study aims to evaluate the process of brain development in neonates using combined amide proton transfer (APT) imaging and conventional magnetization transfer (MT) imaging. Materials and Methods. Case data were reviewed for all patients hospitalized in our institution's neonatal ward. Patients underwent APT and MT imaging (a single protocol) immediately following the routine MR ex...