OBJECTIVE To evaluate the effect of Radix euphorbiae pekinensis extract on the permeability and bioavailability of paclitaxel co-administered orally. METHODS Based on Ussing Chamber and in vivo experiment, the permeability and bioavailability of paclitaxel were evaluated after oral co-administration with radix euphorbiae pekinensis in rats. The contents of paclitaxel in the permeates and the ...

Aphids are associated with loss in yield and quality of pepper crop due to damage they cause the transmission viruses a non-persistent manner. The aim study was determine potential border crops intercrops management aphids hot production. Field experiments were carried out for two seasons 2018/2019 at Rubona Research station, Huye District, Rwanda. Maize (Zea Mays L.), sorghum (Sorghum bicolor ...

Linseed, one of the oldest cultivated crops, is again gaining in importance, mainly due to its nutritional benefi ts and biomedical applications. Th erefore, it is expected that herbivores will also exist in greater abundance. Among them the fl ea beetle, Aphthona euphorbiae Schrank and Longitarsus parvulus Paykull are considered to be serious pests of fl ax grown for fi bre and seeds in Europe...

The tomato (Solanum lycopersicum) Mi-1 gene encodes a protein with putative coiled-coil nucleotide-binding site and leucine-rich repeat motifs. Mi-1 confers resistance to root-knot nematodes (Meloidogyne spp.), potato aphids (Macrosiphum euphorbiae), and sweet potato whitefly (Bemisia tabaci). To identify genes required in the Mi-1-mediated resistance to nematodes and aphids, we used tobacco ra...

According to traditional Chinese medicine theories, Euphorbiae Pekinensis Radix and Glycyrrhizae Radix should not be used together in one prescription, because their interaction leads to an unexpected consequence. However, the mechanism remains unclear. The purpose of this study was to find out whether CYP2C9 was involved in this herb-herb interaction by using tolbutamide as a probe substrate i...

In natural habitats plants can be exposed to brief and light contact with neighbouring plants. This mechanical stimulus may represent a cue that induces responses to nearby plants. However, little is known about the effect of touching on plant growth and interaction with insect herbivores. To simulate contact between plants, a soft brush was used to apply light and brief mechanical stimuli to t...

Temperature changes are common in nature and insects are particularly exposed and sensitive to such variations which can be potential stresses, ultimately affecting life history traits and overall fitness. Braconids have been widely used to study the effects of temperature on host-parasitoid interactions and the present work focused on the solitary endoparasitoid Aphidius ervi Haliday (Hymenopt...